NLM Logo

Optic Atrophy, Hereditary, Leber MeSH Descriptor Data 2023


MeSH Heading
Optic Atrophy, Hereditary, Leber
Tree Number(s)
C10.292.700.225.500.400
C10.574.500.662.400
C11.270.564.400
C11.640.451.451.400
C16.320.290.564.400
C16.320.400.630.400
C18.452.660.670
Unique ID
D029242
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D029242
Scope Note
A maternally linked genetic disorder that presents in mid-life as acute or subacute central vision loss leading to central scotoma and blindness. The disease has been associated with missense mutations in the mtDNA, in genes for Complex I, III, and IV polypeptides, that can act autonomously or in association with each other to cause the disease. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/Omim/, MIM#535000 (April 17, 2001))
Entry Term(s)
Hereditary Optic Neuroretinopathy
Leber Hereditary Optic Atrophy
Leber Hereditary Optic Neuropathy
Leber Optic Atrophy
Leber Optic Atrophy and Dystonia
Leber's Disease
Leber's Hereditary Optic Atrophy
Leber's Hereditary Optic Neuropathy
Leber's Optic Atrophy
Leber's Optic Neuropathy
Optic Atrophy, Leber Type
Optic Atrophy, Leber, Hereditary
Previous Indexing
Optic Atrophies, Hereditary (1989-2001)
Optic Atrophy/genetics (1977-1988)
Public MeSH Note
2002; see OPTIC ATROPHIES, HEREDITARY 1999-2001
History Note
2002; use OPTIC ATROPHIES, HEREDITARY 1999-2001
Date Established
2002/01/01
Date of Entry
2001/07/25
Revision Date
2013/07/08
Optic Atrophy, Hereditary, Leber Preferred
page delivered in 0.161s