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Wolfram Syndrome MeSH Descriptor Data 2023


MeSH Heading
Wolfram Syndrome
Tree Number(s)
C09.218.458.341.186.500.750
C10.292.700.225.500.980
C10.574.500.662.980
C10.597.751.418.341.186.500.750
C10.597.751.941.162.625.750
C11.270.564.980
C11.640.451.451.980
C11.966.075.375.750
C12.050.351.968.419.135.875
C12.200.777.419.135.875
C12.950.419.135.875
C16.131.077.299.750
C16.320.290.564.980
C16.320.400.630.980
C18.452.394.750.124.960
C19.246.267.960
C19.700.159.875
Unique ID
D014929
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D014929
Scope Note
A hereditary condition characterized by multiple symptoms including those of DIABETES INSIPIDUS; DIABETES MELLITUS; OPTIC ATROPHY; and DEAFNESS. This syndrome is also known as DIDMOAD (first letter of each word) and is usually associated with VASOPRESSIN deficiency. It is caused by mutations in gene WFS1 encoding wolframin, a 100-kDa transmembrane protein.
Entry Term(s)
DIDMOAD
DIDMOAD Syndrome
DIDMOADUD
Diabetes Insipidus and Mellitus with Optic Atrophy and Deafness
Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness
Wolfram Syndrome 1
Previous Indexing
Deafness (1966-1985)
Diabetes Insipidus (1966-1985)
Diabetes Mellitus, Insulin-Dependent (1984-1985)
Optic Atrophy (1966-1985)
Public MeSH Note
86
History Note
86
Date Established
1986/01/01
Date of Entry
1985/03/11
Revision Date
2021/06/30
Wolfram Syndrome Preferred
Wolfram Syndrome 1 Narrower
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