MeSH Browser

MeSH Heading: Usher Syndromes
Tree Number(s): C09.218.458.341.186.500.500; C09.218.458.341.887.886; C10.597.751.418.341.186.500.500; C10.597.751.418.341.887.886; C10.597.751.941.162.625.500; C11.768.585.658.500.813; C11.966.075.375.500; C16.131.077.299.500; C16.320.290.684.500; C23.888.592.763.393.341.887.886
Unique ID: D052245
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D052245
Scope Note: Autosomal recessive hereditary disorders characterized by congenital SENSORINEURAL HEARING LOSS and RETINITIS PIGMENTOSA. Genetically and symptomatically heterogeneous, clinical classes include type I, type II, and type III. Their severity, age of onset of retinitis pigmentosa and the degree of vestibular dysfunction are variable.
Entry Term(s): Deafness-Retinitis Pigmentosa Syndrome; Dystrophia Retinae Pigmentosa-Dysostosis Syndrome; Graefe-Usher Syndrome; Hallgren Syndrome; Retinitis Pigmentosa And Congenital Deafness; Retinitis Pigmentosa-Deafness Syndrome; Usher Syndrome; Usher Syndrome, Type 1; Usher Syndrome, Type 1A; Usher Syndrome, Type 3; Usher Syndrome, Type I; Usher Syndrome, Type I, French Variety; Usher Syndrome, Type II; Usher Syndrome, Type III; Usher Syndrome, Type IId; Usher's Syndrome
Previous Indexing: Deafness (1972-2005); Hearing Loss, Sensorineural (1983-2005); Retinitis Pigmentosa (1972-2005); Syndrome (1972-2005)
Public MeSH Note: 2006
History Note: 2006
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2013/07/08

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Otorhinolaryngologic Diseases [C09]
- Ear Diseases [C09.218]
  - Hearing Disorders [C09.218.458]
    - Hearing Loss [C09.218.458.341]
      - Deafness [C09.218.458.341.186]
        
        Deaf-Blind Disorders [C09.218.458.341.186.500]
        
        CHARGE Syndrome [C09.218.458.341.186.500.250]
        
        Usher Syndromes [C09.218.458.341.186.500.500]
        
        Wolfram Syndrome [C09.218.458.341.186.500.750]

Otorhinolaryngologic Diseases [C09]
- Ear Diseases [C09.218]
  - Hearing Disorders [C09.218.458]
    - Hearing Loss [C09.218.458.341]
      - Hearing Loss, Sensorineural [C09.218.458.341.887]
        
        Hearing Loss, Central [C09.218.458.341.887.432]
        
        Hearing Loss, Noise-Induced [C09.218.458.341.887.460]
        
        Presbycusis [C09.218.458.341.887.772]
        
        Usher Syndromes [C09.218.458.341.887.886]

Nervous System Diseases [C10]
- Neurologic Manifestations [C10.597]
  - Sensation Disorders [C10.597.751]
    - Hearing Disorders [C10.597.751.418]
      - Hearing Loss [C10.597.751.418.341]
        
        Deafness [C10.597.751.418.341.186]
        
        Deaf-Blind Disorders [C10.597.751.418.341.186.500]
        
        CHARGE Syndrome [C10.597.751.418.341.186.500.250]
        
        Usher Syndromes [C10.597.751.418.341.186.500.500]
        
        Wolfram Syndrome [C10.597.751.418.341.186.500.750]

Nervous System Diseases [C10]
- Neurologic Manifestations [C10.597]
  - Sensation Disorders [C10.597.751]
    - Hearing Disorders [C10.597.751.418]
      - Hearing Loss [C10.597.751.418.341]
        
        Hearing Loss, Sensorineural [C10.597.751.418.341.887]
        
        Hearing Loss, Central [C10.597.751.418.341.887.432]
        
        Hearing Loss, Noise-Induced [C10.597.751.418.341.887.460]
        
        Presbycusis [C10.597.751.418.341.887.772]
        
        Usher Syndromes [C10.597.751.418.341.887.886]

Nervous System Diseases [C10]
- Neurologic Manifestations [C10.597]
  - Sensation Disorders [C10.597.751]
    - Vision Disorders [C10.597.751.941]
      - Blindness [C10.597.751.941.162]
        
        Deaf-Blind Disorders [C10.597.751.941.162.625]
        
        CHARGE Syndrome [C10.597.751.941.162.625.250]
        
        Usher Syndromes [C10.597.751.941.162.625.500]
        
        Wolfram Syndrome [C10.597.751.941.162.625.750]

Eye Diseases [C11]
- Retinal Diseases [C11.768]
  - Retinal Degeneration [C11.768.585]
    - Retinal Dystrophies [C11.768.585.658]
      - Retinitis Pigmentosa [C11.768.585.658.500]
        
        Kearns-Sayre Syndrome [C11.768.585.658.500.627]
        
        Usher Syndromes [C11.768.585.658.500.813]

Eye Diseases [C11]
- Vision Disorders [C11.966]
  - Blindness [C11.966.075]
    - Deaf-Blind Disorders [C11.966.075.375]

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Congenital Abnormalities [C16.131]
  - Abnormalities, Multiple [C16.131.077]
    - Deaf-Blind Disorders [C16.131.077.299]

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
  - Eye Diseases, Hereditary [C16.320.290]
    - Retinitis Pigmentosa [C16.320.290.684]
      - Alstrom Syndrome [C16.320.290.684.249]
      - Usher Syndromes [C16.320.290.684.500]

Pathological Conditions, Signs and Symptoms [C23]
- Signs and Symptoms [C23.888]
  - Neurologic Manifestations [C23.888.592]
    - Sensation Disorders [C23.888.592.763]
      - Hearing Disorders [C23.888.592.763.393]
        
        Hearing Loss [C23.888.592.763.393.341]
        
        Hearing Loss, Sensorineural [C23.888.592.763.393.341.887]
        
        Hearing Loss, Central [C23.888.592.763.393.341.887.432]
        
        Hearing Loss, Noise-Induced [C23.888.592.763.393.341.887.460]
        
        Presbycusis [C23.888.592.763.393.341.887.772]
        
        Usher Syndromes [C23.888.592.763.393.341.887.886]

Usher Syndromes Preferred

Concept UI: M0483844
Scope Note: Autosomal recessive hereditary disorders characterized by congenital SENSORINEURAL HEARING LOSS and RETINITIS PIGMENTOSA. Genetically and symptomatically heterogeneous, clinical classes include type I, type II, and type III. Their severity, age of onset of retinitis pigmentosa and the degree of vestibular dysfunction are variable.
Terms: Usher Syndromes Preferred Term
Term UI T637978
Date04/26/2005
LexicalTag NON
ThesaurusID NLM (2006); Usher Syndrome
Term UI T637979
Date04/26/2005
LexicalTag NON
ThesaurusID; Deafness-Retinitis Pigmentosa Syndrome
Term UI T842646
Date04/18/2013
LexicalTag NON
ThesaurusID GHR (2014); Dystrophia Retinae Pigmentosa-Dysostosis Syndrome
Term UI T842647
Date04/18/2013
LexicalTag NON
ThesaurusID GHR (2014); Retinitis Pigmentosa-Deafness Syndrome
Term UI T782133
Date12/14/2010
LexicalTag NON
ThesaurusID; Hallgren Syndrome
Term UI T842649
Date04/18/2013
LexicalTag EPO
ThesaurusID GHR (2014); Usher's Syndrome
Term UI T842650
Date04/18/2013
LexicalTag EPO
ThesaurusID GHR (2014); Graefe-Usher Syndrome
Term UI T842648
Date04/18/2013
LexicalTag EPO
ThesaurusID GHR (2014)

Usher Syndrome, Type I Narrower

Usher Syndrome, Type III Narrower

Usher Syndrome, Type II Narrower

Usher Syndromes MeSH Descriptor Data 2025