MeSH Browser

MeSH Heading: Telomeric Repeat Binding Protein 1
Tree Number(s): A11.284.430.106.279.345.190.160.845.500.500; D12.776.260.735.750; D12.776.660.235.700.750; D12.776.664.981.500
Unique ID: D035321
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D035321
Scope Note: A ubiquitously expressed telomere-binding protein that is present at TELOMERES throughout the CELL CYCLE. It is a suppressor of telomere elongation and may be involved in stabilization of telomere length. It is structurally different from TELOMERIC REPEAT BINDING PROTEIN 2 in that it contains acidic N-terminal amino acid residues.
Entry Term(s): PIN2 Protein; TERF1 Protein; TRF1 Protein; TTAGGG Repeat Binding Factor 1
Previous Indexing: DNA-Binding Proteins (1997-2002)
Public MeSH Note: 2003; TRF1 PROTEIN was indexed under DNA-BINDING PROTEINS 1997-2002
History Note: 2003; for TRF1 PROTEIN use TELOMERE-BINDING PROTEINS (NM) 1997-2002;
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2021/05/10

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0194748
Scope Note: A ubiquitously expressed telomere-binding protein that is present at TELOMERES throughout the CELL CYCLE. It is a suppressor of telomere elongation and may be involved in stabilization of telomere length. It is structurally different from TELOMERIC REPEAT BINDING PROTEIN 2 in that it contains acidic N-terminal amino acid residues.
Terms: Telomeric Repeat Binding Protein 1 Preferred Term
Term UI T473205
Date12/11/2001
LexicalTag NON
ThesaurusID NLM (2003); TERF1 Protein
Term UI T473206
Date12/11/2001
LexicalTag ACX
ThesaurusID NLM (2003); TRF1 Protein
Term UI T224753
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2003); TTAGGG Repeat Binding Factor 1
Term UI T473213
Date12/11/2001
LexicalTag ACX
ThesaurusID NLM (2003)

Telomeric Repeat Binding Protein 1 MeSH Descriptor Data 2025