MeSH Browser

MeSH Heading: Telomeric Repeat Binding Protein 2
Tree Number(s): A11.284.430.106.279.345.190.160.845.500.750; D12.776.260.735.875; D12.776.660.235.700.875; D12.776.664.981.750; G05.360.160.845.500.500
Unique ID: D035341
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D035341
Scope Note: A ubiquitously expressed telomere-binding protein that is present at TELOMERES throughout the cell cycle. It is a suppressor of telomere elongation and may be involved in stabilization of telomere length. It is structurally different from TELOMERIC REPEAT BINDING PROTEIN 1 in that it contains basic N-terminal amino acid residues.
Entry Term(s): TERF2 Protein; TRBF2 Protein; TRF2 Protein; Trf2 Gene Product
Previous Indexing: DNA-Binding Proteins (1998-2002)
Public MeSH Note: 2003; TRF2 PROTEIN (now TELOMERIC REPEAT BINDING PROTEIN 2) was indexed under DNA-BINDING PROTEINS 1998-2002
History Note: 2003; use TELOMERIC REPEAT BINDING PROTEIN 2 (NM) 1998-2002
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2021/05/10

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0282405
Scope Note: A ubiquitously expressed telomere-binding protein that is present at TELOMERES throughout the cell cycle. It is a suppressor of telomere elongation and may be involved in stabilization of telomere length. It is structurally different from TELOMERIC REPEAT BINDING PROTEIN 1 in that it contains basic N-terminal amino acid residues.
Terms: Telomeric Repeat Binding Protein 2 Preferred Term
Term UI T473267
Date12/12/2001
LexicalTag NON
ThesaurusID NLM (2003); Trf2 Gene Product
Term UI T312409
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2003); TRF2 Protein
Term UI T312410
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2003); TRBF2 Protein
Term UI T473268
Date12/12/2001
LexicalTag ACX
ThesaurusID NLM (2003); TERF2 Protein
Term UI T473269
Date12/12/2001
LexicalTag ACX
ThesaurusID NLM (2003)

Telomeric Repeat Binding Protein 2 MeSH Descriptor Data 2025