MeSH Browser

MeSH Heading: Ephrin-B3
Tree Number(s): D12.644.276.500.800; D12.776.467.500.800; D12.776.543.287.800; D23.529.500.800
Unique ID: D036389
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D036389
Scope Note: A transmembrane domain containing ephrin. Although originally found to be specific for the EPHB3 RECEPTOR it has since been shown to bind a variety of EPH FAMILY RECEPTORS. During embryogenesis ephrin-B3 is expressed at high levels in the ventral neural tube. In adult tissues, it is found primarily in the BRAIN and HEART.
Entry Term(s): EFNB3; EPLG8 Gene Product; LERK-8; LERK-8 Protein
Previous Indexing: Membrane Proteins (1997-2002)
Public MeSH Note: 2003; EPHRIN-B3 was indexed under MEMBRANE PROTEINS 1998-2002; LERK-8 PROTEIN (now EPHRIN-B3) was indexed under MEMBRANE PROTEINS 1997-2002
History Note: 2003; use EPHRIN-B3 (NM) 1997-2002
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2006/07/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0286807
Scope Note: A transmembrane domain containing ephrin. Although originally found to be specific for the EPHB3 RECEPTOR it has since been shown to bind a variety of EPH FAMILY RECEPTORS. During embryogenesis ephrin-B3 is expressed at high levels in the ventral neural tube. In adult tissues, it is found primarily in the BRAIN and HEART.
Terms: Ephrin-B3 Preferred Term
Term UI T316812
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003); EPLG8 Gene Product
Term UI T305484
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2003); LERK-8
Term UI T305485
Date01/01/1955
LexicalTag ACR
ThesaurusID NLM (2003); LERK-8 Protein
Term UI T305486
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2003); EFNB3
Term UI T434752
Date01/31/2001
LexicalTag ACR
ThesaurusID NLM (2003)

Ephrin-B3 MeSH Descriptor Data 2025