MeSH Browser

MeSH Heading: Prokaryotic Initiation Factor-3
Tree Number(s): D12.776.835.725.934.750
Unique ID: D039665
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D039665
Scope Note: A prokaryotic initiation factor that plays a role in recycling of ribosomal subunits for a new round of translational initiation. It binds to 16S RIBOSOMAL RNA and stimulates the dissociation of vacant 70S ribosomes. It may also be involved in the preferential binding of initiator tRNA to the 30S initiation complex.
Entry Term(s): Initiation Factor IF-3; Peptide Initiation Factor 3; Peptide Initiation Factor IF-3; Prokaryotic Peptide Initiation Factor-3; TIF IF3; Translation Initiation Factor 3
Registry Numbers: 0
Previous Indexing: Peptide Initiation Factors (1979-2002)
Public MeSH Note: 2003; PEPTIDE INITIATION FACTOR 3 (now PROKARYOTIC INITIATION FACTOR-3) was indexed under PEPTIDE INITIATION FACTORS 1979-2002; TIF IF3 & TRANSLATION INITIATION FACTOR 3 were indexed under PEPTIDE INITIATION FACTORS 1994-2002
History Note: 2003; use PROKARYOTIC INITIATION FACTOR-3 (NM) 1979-2002; for TIF IF3 & TRANSLATION INITIATION FACTOR 3 use EUKARYOTIC INITIATION FACTOR-3 (NM) 1994-2002
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2005/07/11

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0078903
Registry Numbers: 0
Scope Note: A prokaryotic initiation factor that plays a role in recycling of ribosomal subunits for a new round of translational initiation. It binds to 16S RIBOSOMAL RNA and stimulates the dissociation of vacant 70S ribosomes. It may also be involved in the preferential binding of initiator tRNA to the 30S initiation complex.
Terms: Prokaryotic Initiation Factor-3 Preferred Term
Term UI T488802
Date04/05/2002
LexicalTag NON
ThesaurusID NLM (2003); Initiation Factor IF-3
Term UI T108904
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2003); Peptide Initiation Factor 3
Term UI T108906
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003); Peptide Initiation Factor IF-3
Term UI T489322
Date04/12/2002
LexicalTag ACX
ThesaurusID NLM (2003); Prokaryotic Peptide Initiation Factor-3
Term UI T488278
Date04/01/2002
LexicalTag NON
ThesaurusID NLM (2003); TIF IF3
Term UI T207967
Date01/01/1955
LexicalTag ACR
ThesaurusID NLM (2003); Translation Initiation Factor 3
Term UI T207971
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003)

Prokaryotic Initiation Factor-3 MeSH Descriptor Data 2024