MeSH Browser

MeSH Heading: Prokaryotic Initiation Factor-1
Tree Number(s): D12.776.835.725.934.374
Unique ID: D039861
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D039861
Scope Note: The smallest of the three prokaryotic initiation factors with a molecular size of approximately 8 kD. It binds near the A-site of the 30S subunit of RIBOSOMES and may play a role in preventing premature addition of aminoacyl-tRNA-linked PEPTIDE ELONGATION FACTOR TU to the ribosome during the initiation of a peptide chain (PEPTIDE CHAIN INITIATION, TRANSLATIONAL).
Entry Term(s): Initiation Factor IF-1; Peptide Initiation Factor IF-1; Peptide Initiation Factor-1, Prokaryotic; Prokaryotic Peptide Initiation Factor-1
Registry Numbers: 0
Previous Indexing: Eukaryotic Initiation Factor-1 (1989-2002); Peptide Initiation Factors (1978-2002)
Public MeSH Note: 2003; for IF-1see EIF-1 1990-2002
History Note: 2003; for IF-1 use EUKARYOTIC INITIATION FACTOR-1 1990-2002
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2004/07/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0419356
Registry Numbers: 0
Scope Note: The smallest of the three prokaryotic initiation factors with a molecular size of approximately 8 kD. It binds near the A-site of the 30S subunit of RIBOSOMES and may play a role in preventing premature addition of aminoacyl-tRNA-linked PEPTIDE ELONGATION FACTOR TU to the ribosome during the initiation of a peptide chain (PEPTIDE CHAIN INITIATION, TRANSLATIONAL).
Terms: Prokaryotic Initiation Factor-1 Preferred Term
Term UI T488803
Date04/05/2002
LexicalTag NON
ThesaurusID NLM (2003); Initiation Factor IF-1
Term UI T047392
Date05/10/1989
LexicalTag ACX
ThesaurusID NLM (1990); Peptide Initiation Factor IF-1
Term UI T489321
Date04/12/2002
LexicalTag ACX
ThesaurusID NLM (2003); Peptide Initiation Factor-1, Prokaryotic
Term UI T488804
Date04/05/2002
LexicalTag NON
ThesaurusID NLM (2003); Prokaryotic Peptide Initiation Factor-1
Term UI T489320
Date04/12/2002
LexicalTag NON
ThesaurusID NLM (2003)

Prokaryotic Initiation Factor-1 MeSH Descriptor Data 2024