Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

Peptide Chain Initiation, Translational MeSH Descriptor Data 2026


MeSH Heading
Peptide Chain Initiation, Translational
Tree Number(s)
G02.111.660.871.650
G03.734.871.650
Unique ID
D010442
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D010442
Annotation
coordinate with specific peptide; for protein biosynthesis on the ribosome only; for non-ribosomal biosynthesis use PEPTIDE BIOSYNTHESIS, NUCLEIC ACID-INDEPENDENT
Scope Note
A process of GENETIC TRANSLATION whereby the formation of a peptide chain is started. It includes assembly of the RIBOSOME components, the MESSENGER RNA coding for the polypeptide to be made, INITIATOR TRNA, and PEPTIDE INITIATION FACTORS; and placement of the first amino acid in the peptide chain. The details and components of this process are unique for prokaryotic protein biosynthesis and eukaryotic protein biosynthesis.
Entry Term(s)
Chain Initiation, Peptide, Translational
Protein Biosynthesis Initiation
Protein Chain Initiation, Translational
Protein Translation Initiation
Translation Initiation, Genetic
Translation Initiation, Protein
Translational Initiation, Protein
Translational Peptide Chain Initiation
Previous Indexing
Peptides/biosynthesis (1966-1970)
See Also
Codon, Initiator
Peptide Initiation Factors
Protein Synthesis Inhibitors
Public MeSH Note
2005; see PEPTIDE CHAIN INITIATION 1973-2004
History Note
73(71)
Date Introduced
1973/01/01
Last Updated
2016/07/01
Peptide Chain Initiation, Translational Preferred
page delivered in 0.138s