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Prokaryotic Initiation Factor-2 MeSH Descriptor Data 2026
The largest of the three prokaryotic initiation factors with a molecular size of approximately 80 kD. It functions in the transcription initiation process by promoting the binding of formylmethionine-tRNA to the P-site of the 30S ribosome and by preventing the incorrect binding of elongator tRNA to the translation initiation site.
Entry Term(s)
IF2 Protein
Initiation Factor-2
Peptide Initiation Factor 2
Peptide Initiation Factor IF-2
Translational Initiation Factor 2
infB Gene Product
infB Protein
Registry Numbers
0
Previous Indexing
Peptide Initiation Factors (1990-2002)
Public MeSH Note
2003; PROKARYOTIC INITIATION FACTOR-2 was indexed under PEPTIDE INTIATION FACTORS 1990-2002; TRANSLATIONAL INITIATION FACTOR 2 was indexed under PEPTIDE INITIATION FACTORS 1997-2002
History Note
2003; use PROKARYOTIC INITIATION FACTOR-2 (NM) 1990-2002
The largest of the three prokaryotic initiation factors with a molecular size of approximately 80 kD. It functions in the transcription initiation process by promoting the binding of formylmethionine-tRNA to the P-site of the 30S ribosome and by preventing the incorrect binding of elongator tRNA to the translation initiation site.