MeSH Browser

MeSH Heading: Prokaryotic Initiation Factor-2
Tree Number(s): D12.776.835.725.934.562
Unique ID: D039881
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D039881
Scope Note: The largest of the three prokaryotic initiation factors with a molecular size of approximately 80 kD. It functions in the transcription initiation process by promoting the binding of formylmethionine-tRNA to the P-site of the 30S ribosome and by preventing the incorrect binding of elongator tRNA to the translation initiation site.
Entry Term(s): IF2 Protein; Initiation Factor-2; Peptide Initiation Factor 2; Peptide Initiation Factor IF-2; Translational Initiation Factor 2; infB Gene Product; infB Protein
Registry Numbers: 0
Previous Indexing: Peptide Initiation Factors (1990-2002)
Public MeSH Note: 2003; PROKARYOTIC INITIATION FACTOR-2 was indexed under PEPTIDE INTIATION FACTORS 1990-2002; TRANSLATIONAL INITIATION FACTOR 2 was indexed under PEPTIDE INITIATION FACTORS 1997-2002
History Note: 2003; use PROKARYOTIC INITIATION FACTOR-2 (NM) 1990-2002
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 1955/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0176255
Registry Numbers: 0
Scope Note: The largest of the three prokaryotic initiation factors with a molecular size of approximately 80 kD. It functions in the transcription initiation process by promoting the binding of formylmethionine-tRNA to the P-site of the 30S ribosome and by preventing the incorrect binding of elongator tRNA to the translation initiation site.
Terms: Prokaryotic Initiation Factor-2 Preferred Term
Term UI T488276
Date04/01/2002
LexicalTag NON
ThesaurusID NLM (2003); IF2 Protein
Term UI T432204
Date01/03/2001
LexicalTag ACX
ThesaurusID NLM (2003); infB Gene Product
Term UI T206256
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2003); infB Protein
Term UI T206257
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2003); Initiation Factor-2
Term UI T206258
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003); Peptide Initiation Factor 2
Term UI T206260
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003); Peptide Initiation Factor IF-2
Term UI T206259
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2003); Translational Initiation Factor 2
Term UI T304454
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003)

Prokaryotic Initiation Factor-2 MeSH Descriptor Data 2024