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Vascular Endothelial Growth Factor Receptor-2 MeSH Descriptor Data 2026
A 200-230-kDa tyrosine kinase receptor for vascular endothelial growth factors found primarily in endothelial and hematopoietic cells and their precursors. VEGFR-2 is important for vascular and hematopoietic development, and mediates almost all endothelial cell responses to VEGF.
Entry Version
VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPT 2
Entry Term(s)
Fetal Liver Kinase-1
Flk-1 Protein
Flk-1 Receptor Tyrosine Kinase
KDR Tyrosine Kinase
Kinase Insert Domain Receptor
VEGF Receptor Flk-1
VEGF Receptor KDR
VEGFR-2
Registry Numbers
EC 2.7.10.1
Previous Indexing
Protein-Tyrosine Kinase (1993)
Receptor Protein-Tyrosine Kinases (1994-2002)
Receptors, Growth Factor (1993-2002)
Public MeSH Note
2003; VEGFR-2 was indexed under RECEPTORS, PROTEIN-TYROSINE KINASES 1996-2002
History Note
2003; for FETAL LIVER KINASE-1, KDR TYROSINE KINASE, FLK-1 RECEPTOR TYROSINE KINASE & FLK-1 PROTEIN use RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR 1993-2002; for VEGFR-2 use RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR 1996-2002
A 200-230-kDa tyrosine kinase receptor for vascular endothelial growth factors found primarily in endothelial and hematopoietic cells and their precursors. VEGFR-2 is important for vascular and hematopoietic development, and mediates almost all endothelial cell responses to VEGF.