MeSH Browser

MeSH Heading: Methylmalonyl-CoA Decarboxylase
Tree Number(s): D08.811.520.224.125.387
Unique ID: D043586
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D043586
Scope Note: A carboxy-lyase that catalyzes the DECARBOXYLATION of (S)-2-Methyl-3-oxopropanoyl-CoA to propanoyl-CoA. In microorganisms the reaction can be coupled to the vectorial transport of SODIUM ions across the cytoplasmic membrane.
Entry Term(s): (S)-methylmalonyl-CoA Decarboxylase (Sodium-Transporting); Methylmalonyl-Coenzyme A Decarboxylase
Registry Numbers: EC 7.2.4.3
Related Numbers: 37289-44-4
Previous Indexing: Carboxy-Lyases (1983-2003); Propionates (1984-2003)
See Also: Propionic Acidemia
Public MeSH Note: 2004; PROPIONYL-COA CARBOXYLASE was indexed under CARBOXY-LYASES 1983-2003 & under PROPIONATES 1975-1982
History Note: 2004; use METHYLMALONYL-COA DECARBOXYLASE (NM) 1980-2003
Entry Combination: deficiency:Propionic Acidemia
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2023/02/26

Entry Combination: deficiency:Propionic Acidemia
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0078512
Registry Numbers: EC 7.2.4.3
Related Numbers: 37289-44-4
Scope Note: A carboxy-lyase that catalyzes the DECARBOXYLATION of (S)-2-Methyl-3-oxopropanoyl-CoA to propanoyl-CoA. In microorganisms the reaction can be coupled to the vectorial transport of SODIUM ions across the cytoplasmic membrane.
Terms: Methylmalonyl-CoA Decarboxylase Preferred Term
Term UI T108513
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2004); (S)-methylmalonyl-CoA Decarboxylase (Sodium-Transporting)
Term UI T001124728
Date09/13/2022
LexicalTag ABX
ThesaurusID NLM (2024); Methylmalonyl-Coenzyme A Decarboxylase
Term UI T001124729
Date09/13/2022
LexicalTag NON
ThesaurusID NLM (2024)

Methylmalonyl-CoA Decarboxylase MeSH Descriptor Data 2025