MeSH Browser

MeSH Heading: Receptors, Calcium-Sensing
Tree Number(s): D12.776.543.750.695.115
Unique ID: D044169
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D044169
Annotation: CALCIUM-BINDING PROTEINS is also available
Scope Note: A class of G-protein-coupled receptors that react to varying extracellular CALCIUM levels. Calcium-sensing receptors in the PARATHYROID GLANDS play an important role in the maintenance of calcium HOMEOSTASIS by regulating the release of PARATHYROID HORMONE. They differ from INTRACELLULAR CALCIUM-SENSING PROTEINS which sense intracellular calcium levels.
Entry Term(s): CASR Protein; Ca-Sensing Receptors; Ca2+-Sensing Receptor; Calcium Receptors; Calcium-Sensing Receptor; Calcium-Sensing Receptor Protein; Calcium-Sensing Receptors; Extracellular Calcium-Ion Sensing Receptor; Parathyroid Calcium-Sensing Receptor; Receptor, Ca-Sensing; Receptors, Calcium
Registry Numbers: 0
Previous Indexing: Receptors, Cell Surface (1994-2003)
See Also: Intracellular Calcium-Sensing Proteins
Public MeSH Note: 2004; use RECEPTORS, CALCIUM-SENSING (NM) 1994-2003; for CALCIUM RECEPTORS see CALCIUM-BINDING PROTEINS 1982-2003; for RECEPTORS, CALCIUM see CALCIUM-BINDING PROTEINS 1996-2003
History Note: 2004; CALCIUM-SENSING RECEPTOR (now RECEPTORS, CALCIUM-SENSING) was indexed under RECEPTORS, CELL SURFACE; for CALCIUM RECEPTORS use CALCIUM-BINDING PROTEINS 1982-2003; for RECEPTORS, CALCIUM use CALCIUM-BINDING PROTEINS 1996-2003
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2016/06/17

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, G-Protein-Coupled [D12.776.543.750.695]
        
        Apelin Receptors [D12.776.543.750.695.006]
        
        Calcitonin Receptor-Like Protein [D12.776.543.750.695.011]
        
        Frizzled Receptors [D12.776.543.750.695.017]
        
        Glucagon-Like Peptide Receptors [D12.776.543.750.695.021]
        
        Receptors, Kisspeptin-1 [D12.776.543.750.695.022]
        
        Orexin Receptors [D12.776.543.750.695.023]
        
        Receptor, Anaphylatoxin C5a [D12.776.543.750.695.024]
        
        Receptor, PAR-2 [D12.776.543.750.695.035]
        
        Receptors, Adrenomedullin [D12.776.543.750.695.041]
        
        Receptors, Angiotensin [D12.776.543.750.695.047]
        
        Receptors, Bombesin [D12.776.543.750.695.070]
        
        Receptors, Bradykinin [D12.776.543.750.695.080]
        
        Receptors, Calcitonin [D12.776.543.750.695.100]
        
        Receptors, Calcitonin Gene-Related Peptide [D12.776.543.750.695.105]
        
        Receptors, Calcium-Sensing [D12.776.543.750.695.115]
        
        Receptors, Cannabinoid [D12.776.543.750.695.125]
        
        Receptors, Catecholamine [D12.776.543.750.695.150]
        
        Receptors, Chemokine [D12.776.543.750.695.160]
        
        Receptors, Cholecystokinin [D12.776.543.750.695.170]
        
        Receptors, Corticotropin-Releasing Hormone [D12.776.543.750.695.180]
        
        Receptors, Eicosanoid [D12.776.543.750.695.200]
        
        Receptors, Endothelin [D12.776.543.750.695.220]
        
        Receptors, Formyl Peptide [D12.776.543.750.695.235]
        
        Receptors, FSH [D12.776.543.750.695.250]
        
        Receptors, GABA-B [D12.776.543.750.695.300]
        
        Receptors, Galanin [D12.776.543.750.695.315]
        
        Receptors, Ghrelin [D12.776.543.750.695.322]
        
        Receptors, Glucagon [D12.776.543.750.695.330]
        
        Receptors, Histamine H1 [D12.776.543.750.695.350]
        
        Receptors, Histamine H2 [D12.776.543.750.695.355]
        
        Receptors, Histamine H4 [D12.776.543.750.695.358]
        
        Receptors, Islet Amyloid Polypeptide [D12.776.543.750.695.360]
        
        Receptors, LH [D12.776.543.750.695.400]
        
        Receptors, LHRH [D12.776.543.750.695.410]
        
        Receptors, Lysophospholipid [D12.776.543.750.695.420]
        
        Receptors, Melanocortin [D12.776.543.750.695.430]
        
        Receptors, Melatonin [D12.776.543.750.695.440]
        
        Receptors, Metabotropic Glutamate [D12.776.543.750.695.450]
        
        Receptors, Muscarinic [D12.776.543.750.695.475]
        
        Receptors, Neuropeptide Y [D12.776.543.750.695.500]
        
        Receptors, Neurotensin [D12.776.543.750.695.550]
        
        Receptors, Odorant [D12.776.543.750.695.600]
        
        Receptors, Opioid [D12.776.543.750.695.620]
        
        Receptors, Oxytocin [D12.776.543.750.695.630]
        
        Receptors, Parathyroid Hormone [D12.776.543.750.695.650]
        
        Receptors, Pheromone [D12.776.543.750.695.660]
        
        Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide [D12.776.543.750.695.665]
        
        Receptors, Purinergic [D12.776.543.750.695.700]
        
        Receptors, Serotonin [D12.776.543.750.695.800]
        
        Receptors, Somatostatin [D12.776.543.750.695.850]
        
        Receptors, Tachykinin [D12.776.543.750.695.862]
        
        Receptors, Thrombin [D12.776.543.750.695.875]
        
        Receptors, Vasopressin [D12.776.543.750.695.910]
        
        Rhodopsin [D12.776.543.750.695.955]
        
        Taste Receptors, Type 2 [D12.776.543.750.695.966]
        
        Xenotropic and Polytropic Retrovirus Receptor [D12.776.543.750.695.977]

Receptors, Calcium-Sensing Preferred

Concept UI: M0225065
Registry Numbers: 0
Scope Note: A class of G-protein-coupled receptors that react to varying extracellular CALCIUM levels. Calcium-sensing receptors in the PARATHYROID GLANDS play an important role in the maintenance of calcium HOMEOSTASIS by regulating the release of PARATHYROID HORMONE. They differ from INTRACELLULAR CALCIUM-SENSING PROTEINS which sense intracellular calcium levels.
Terms: Receptors, Calcium-Sensing Preferred Term
Term UI T530006
Date01/09/2003
LexicalTag NON
ThesaurusID NLM (2004); Receptors, Calcium
Term UI T006098
Date04/13/1995
LexicalTag NON
ThesaurusID NLM (1996); CASR Protein
Term UI T255058
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Ca-Sensing Receptors
Term UI T255059
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2004); Ca2+-Sensing Receptor
Term UI T255060
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Calcium-Sensing Receptor Protein
Term UI T255063
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Extracellular Calcium-Ion Sensing Receptor
Term UI T255065
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Receptor, Ca-Sensing
Term UI T255069
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2004); Calcium-Sensing Receptor
Term UI T255070
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Calcium Receptors
Term UI T006097
Date04/27/1981
LexicalTag NON
ThesaurusID UNK (19XX); Calcium-Sensing Receptors
Term UI T636866
Date04/15/2005
LexicalTag NON
ThesaurusID NLM (2006)

Parathyroid Calcium-Sensing Receptor Narrower

Receptors, Calcium-Sensing MeSH Descriptor Data 2025