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Methenyltetrahydrofolate Cyclohydrolase MeSH Descriptor Data 2026


MeSH Heading
Methenyltetrahydrofolate Cyclohydrolase
Tree Number(s)
D08.811.277.151.418
Unique ID
D045064
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D045064
Scope Note
An aminohydrolase that catalyzes the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate. In most higher eucaryotic organisms this enzyme also includes METHYLENETETRAHYDROFOLATE DEHYDROGENASE (NADP) and FORMATE-TETRAHYDROFOLATE LIGASE activities.
Entry Term(s)
5,10-MTHF Cyclohydrolase
5,10-Methenyltetrahydrofolate 5-Hydrolase (Decyclizing)
5,10-Methenyltetrahydrofolate Cyclohydrolase
Registry Numbers
EC 3.5.4.9
Related Numbers
9027-97-8
Previous Indexing
Aminohydrolases (1983-2003)
Hydrolases (1974-1977)
Tetrahydrofolates (1974-1982)
See Also
Formate-Tetrahydrofolate Ligase
Methylenetetrahydrofolate Dehydrogenase (NADP)
Public MeSH Note
2004; METHENYLTETRAHYDRODROFOLATE CYCLOHYDROLASE was indexed under AMINOHYDROLASES 1983-2003, under TETRAHYDROFOLATES 1974-1982, under HYDROLASES 1974-1977
History Note
2004; use METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE (NM) 1980-2003
Date Introduced
2004/01/01
Last Updated
2004/01/01
Methenyltetrahydrofolate Cyclohydrolase Preferred
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