MeSH Browser

MeSH Heading: STAT3 Transcription Factor
Tree Number(s): D12.644.360.024.342.300; D12.776.157.057.186.300; D12.776.476.024.430.300; D12.776.930.840.300
Unique ID: D050796
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050796
Scope Note: A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-6 family members. STAT3 is constitutively activated in a variety of TUMORS and is a major downstream transducer for the CYTOKINE RECEPTOR GP130.
Entry Term(s): APRF Transcription Factor; Acute-Phase Response Factor; IL6-Response Factor; LIF-Response Factor; STAT3 Protein; STAT3a Transcription Factor; STAT3b Transcription Factor; Signal Transducer and Activator of Transcription 3; Stat3alpha Transcription Factor; Stat3beta Transcription Factor
Registry Number: 0
See Also: src Homology Domains
Public MeSH Note: 2006; STAT3 PROTEIN was indexed under DNA-BINDING PROTEINS & TRANSACTIVATORS 1994-2005
History Note: 2006
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/02/18

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0229085
Registry Number: 0
Scope Note: A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-6 family members. STAT3 is constitutively activated in a variety of TUMORS and is a major downstream transducer for the CYTOKINE RECEPTOR GP130.
Terms: STAT3 Transcription Factor Preferred Term
Term UI T628299
Date01/19/2005
LexicalTag ABX
ThesaurusID NLM (2006); LIF-Response Factor
Term UI T241231
LexicalTag ABX
ThesaurusID NLM (2006); Acute-Phase Response Factor
Term UI T241232
LexicalTag NON
ThesaurusID NLM (2006); APRF Transcription Factor
Term UI T628300
Date01/19/2005
LexicalTag ABX
ThesaurusID NLM (2006); Signal Transducer and Activator of Transcription 3
Term UI T624445
Date12/16/2004
LexicalTag NON
ThesaurusID NLM (2006); IL6-Response Factor
Term UI T241230
LexicalTag ABX
ThesaurusID NLM (2006); STAT3 Protein
Term UI T259090
LexicalTag ABX
ThesaurusID NLM (2006)

STAT3 Transcription Factor MeSH Descriptor Data 2023