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STAT5 Transcription Factor MeSH Descriptor Data 2022


MeSH Heading
STAT5 Transcription Factor
Tree Number(s)
D12.644.360.024.342.500
D12.776.157.057.186.500
D12.776.476.024.430.500
D12.776.930.840.500
Unique ID
D050799
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D050799
Scope Note
A signal transducer and activator of transcription that mediates cellular responses to a variety of CYTOKINES. Stat5 activation is associated with transcription of CELL CYCLE regulators such as CYCLIN KINASE INHIBITOR P21 and anti-apoptotic genes such as BCL-2 GENES. Stat5 is constitutively activated in many patients with acute MYELOID LEUKEMIA.
Entry Term(s)
Mammary Gland Factor
Mammary Gland-Specific Nuclear Factor
STAT5 Protein
STAT5a Protein
STAT5a Transcription Factor
STAT5alpha Protein
STAT5b Protein
STAT5b Transcription Factor
STAT5beta Protein
Signal Transducer and Activator of Transcription 5
Signal Transducer and Activator of Transcription 5A
Signal Transducer and Activator of Transcription 5B
Registry Number
0
Public MeSH Note
2006; STAT5 PROTEIN was indexed under DNA-BINDING PROTEINS; MILK PROTEINS; & TRANS-ACTIVATORS 1992-2005
History Note
2006(1992)
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2016/02/18
STAT5 Transcription Factor Preferred
STAT5b Transcription Factor Narrower
STAT5a Transcription Factor Narrower
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