MeSH Browser

MeSH Heading: NF-E2-Related Factor 2
Tree Number(s): D12.776.260.108.737; D12.776.930.127.737
Unique ID: D051267
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051267
Scope Note: A basic-leucine zipper transcription factor that was originally described as a transcriptional regulator controlling expression of the BETA-GLOBIN gene. It may regulate the expression of a wide variety of genes that play a role in protecting cells from oxidative damage.
Entry Term(s): Nfe2l2 Protein; Nuclear Factor (Erythroid-Derived 2)-Like 2 Protein; Nuclear Factor E2-Related Factor 2
See Also: Antioxidant Response Elements
Public MeSH Note: 2006; NF-E2-RELATED FACTOR 2 was indexed under DNA-BINDING PROTEINS & TRANS-ACTIVATORS 1994-2005
History Note: 2006(1994)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2012/07/03

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0237441
Scope Note: A basic-leucine zipper transcription factor that was originally described as a transcriptional regulator controlling expression of the BETA-GLOBIN gene. It may regulate the expression of a wide variety of genes that play a role in protecting cells from oxidative damage.
Terms: NF-E2-Related Factor 2 Preferred Term
Term UI T267446
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2006); Nfe2l2 Protein
Term UI T629001
Date01/28/2005
LexicalTag ACX
ThesaurusID NLM (2006); Nuclear Factor (Erythroid-Derived 2)-Like 2 Protein
Term UI T635167
Date04/05/2005
LexicalTag NON
ThesaurusID NLM (2006); Nuclear Factor E2-Related Factor 2
Term UI T820078
Date03/27/2012
LexicalTag NON
ThesaurusID NLM (2013)

NF-E2-Related Factor 2 MeSH Descriptor Data 2025