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A family of structurally-related DNA helicases that play an essential role in the maintenance of genome integrity. RecQ helicases were originally discovered in E COLI and are highly conserved across both prokaryotic and eukaryotic organisms. Genetic mutations that result in loss of RecQ helicase activity gives rise to disorders that are associated with CANCER predisposition and premature aging.
2007: RECQ HELICASES was indexed under ADENOSINE TRIPHOSPHATASES & DNA HELICASES 1990-2006; RECQ4 HELICASE was indexed under DNA HELICASES 2002-2006; DNA HELICASE RECQL was indexed under DNA HELICASES & ADENOSINE TRIPHOSPHATASES 1994-2006; RECQ5 HELICASE was indexed under DNA HELICASES 1999-2006
A family of structurally-related DNA helicases that play an essential role in the maintenance of genome integrity. RecQ helicases were originally discovered in E COLI and are highly conserved across both prokaryotic and eukaryotic organisms. Genetic mutations that result in loss of RecQ helicase activity gives rise to disorders that are associated with CANCER predisposition and premature aging.