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Transforming Growth Factor beta1 MeSH Descriptor Data 2022


MeSH Heading
Transforming Growth Factor beta1
Tree Number(s)
D12.644.276.374.687.100
D12.644.276.954.775.100
D12.776.467.374.687.100
D12.776.467.942.775.100
D23.529.374.687.100
D23.529.942.775.100
Unique ID
D053773
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053773
Scope Note
A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.
Entry Term(s)
TGF-beta-1
TGF-beta1
TGF-beta1 Latency-Associated Protein
TGF-beta1LAP
Transforming Growth Factor beta 1 Latency Associated Peptide
Transforming Growth Factor beta I
Transforming Growth Factor-beta1
Registry Number
0
Public MeSH Note
2007; TRANSFORMING GROWTH FACTOR BETA1 was indexed under TRANSFORMING GROWTH FACTOR 2000-2006; TRANSFORMING GROWTH FACTOR BETA 1 LATENCY ASSOCIATED PEPTIDE was indexed under TRANSFORMING GROWTH FACTOR 1992-2006; TRANSFORMING GROWTH FACTOR BETA I was indexed under PROTEINS 2005-2006
History Note
2007(1992)
Entry Combination
deficiency:Camurati-Engelmann Syndrome
Date Established
2007/01/01
Date of Entry
2006/07/05
Revision Date
2020/02/21
Transforming Growth Factor beta1 Preferred
Transforming Growth Factor beta 1 Latency Associated Peptide Narrower
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