MeSH Browser

MeSH Heading: Transforming Growth Factor beta3
Tree Number(s): D12.644.276.374.687.300; D12.644.276.954.775.300; D12.776.467.374.687.300; D12.776.467.942.775.300; D23.529.942.775.300
Unique ID: D053782
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D053782
Scope Note: A TGF-beta subtype that plays role in regulating epithelial-mesenchymal interaction during embryonic development. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta3 and TGF-beta3 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
Entry Term(s): TGF-beta-3; TGF-beta3; TGF-beta3 Latency-Associated Protein; TGF-beta3LAP; TGFB3; Transforming Growth Factor beta 3 Latency Associated Peptide
Public MeSH Note: 2007; TRANSFORMING GROWTH FACTOR BETA3 was indexed under TRANSFORMING GROWTH FACTORS 2000-2003
History Note: 2007(2000)
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2015/06/02

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0358023
Scope Note: A TGF-beta subtype that plays role in regulating epithelial-mesenchymal interaction during embryonic development. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta3 and TGF-beta3 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
Terms: Transforming Growth Factor beta3 Preferred Term
Term UI T410589
Date03/29/2000
LexicalTag NON
ThesaurusID NLM (2007); TGF-beta3
Term UI T408329
Date03/01/2000
LexicalTag ABX
ThesaurusID NLM (2007); TGF-beta-3
Term UI T416781
Date06/15/2000
LexicalTag ABX
ThesaurusID NLM (2007); TGFB3
Term UI T451612
Date06/20/2001
LexicalTag ABX
ThesaurusID NLM (2007)

Transforming Growth Factor beta3 MeSH Descriptor Data 2025