MeSH Browser

MeSH Heading: Calcium-Calmodulin-Dependent Protein Kinase Type 1
Tree Number(s): D08.811.913.696.620.682.700.125.100; D12.776.476.563.125.100
Unique ID: D054729
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D054729
Scope Note: A monomeric calcium-calmodulin-dependent protein kinase subtype that is expressed in a broad variety of mammalian cell types. Its expression is regulated by the action of CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE. Several isoforms of this enzyme subtype are encoded by distinct genes.
Entry Term(s): CaM Kinase I; CaM Kinase I alpha; CaM Kinase I beta; CaM Kinase I delta; CaM Kinase I gamma; CaMK-Like CREB Kinase III; Calcium-Calmodulin-Dependent Protein Kinase Type 1 alpha Isoform; Calcium-Calmodulin-Dependent Protein Kinase Type 1 beta Isoform; Calcium-Calmodulin-Dependent Protein Kinase Type 1 delta Isoform; Calcium-Calmodulin-Dependent Protein Kinase Type 1 gamma Isoform; Calcium-Calmodulin-Dependent Protein Kinase Type 1A; Calcium-Calmodulin-Dependent Protein Kinase Type 1B; Calcium-Calmodulin-Dependent Protein Kinase Type 1D; Calcium-Calmodulin-Dependent Protein Kinase Type 1G; Calcium-Calmodulin-Dependent Protein Kinase Type 1alpha; Calcium-Calmodulin-Dependent Protein Kinase Type 1beta; Calcium-Calmodulin-Dependent Protein Kinase Type 1delta; Calcium-Calmodulin-Dependent Protein Kinase Type 1gamma; Calcium-Dependent CaM Kinase I; Calmodulin-Dependent Protein Kinase I; CamKI-Like Protein Kinase; Pregnancy Upregulated Non-Ubiquitously Expressed CaM Kinase
Related Numbers: EC 2.7.11.17
Public MeSH Note: 2008; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1 was indexed under CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES 1997-2007
History Note: 2008(1994)
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2021/05/20

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Transferases [D08.811.913]
    - Phosphotransferases [D08.811.913.696]
      - Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
        
        Protein Kinases [D08.811.913.696.620.682]
        
        Protein Serine-Threonine Kinases [D08.811.913.696.620.682.700]
        
        Calcium-Calmodulin-Dependent Protein Kinases [D08.811.913.696.620.682.700.125]
        
        Calcium-Calmodulin-Dependent Protein Kinase Kinase [D08.811.913.696.620.682.700.125.049]
        
        Calcium-Calmodulin-Dependent Protein Kinase Type 1 [D08.811.913.696.620.682.700.125.100]
        
        Calcium-Calmodulin-Dependent Protein Kinase Type 2 [D08.811.913.696.620.682.700.125.200]
        
        Calcium-Calmodulin-Dependent Protein Kinase Type 4 [D08.811.913.696.620.682.700.125.350]
        
        Death-Associated Protein Kinases [D08.811.913.696.620.682.700.125.387]
        
        Elongation Factor 2 Kinase [D08.811.913.696.620.682.700.125.425]
        
        Myosin-Light-Chain Kinase [D08.811.913.696.620.682.700.125.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - Protein Serine-Threonine Kinases [D12.776.476.563]
      - Calcium-Calmodulin-Dependent Protein Kinases [D12.776.476.563.125]
        
        Calcium-Calmodulin-Dependent Protein Kinase Kinase [D12.776.476.563.125.049]
        
        Calcium-Calmodulin-Dependent Protein Kinase Type 1 [D12.776.476.563.125.100]
        
        Calcium-Calmodulin-Dependent Protein Kinase Type 2 [D12.776.476.563.125.200]
        
        Calcium-Calmodulin-Dependent Protein Kinase Type 4 [D12.776.476.563.125.350]
        
        Death-Associated Protein Kinases [D12.776.476.563.125.387]
        
        Elongation Factor 2 Kinase [D12.776.476.563.125.425]
        
        Myosin-Light-Chain Kinase [D12.776.476.563.125.500]

Calcium-Calmodulin-Dependent Protein Kinase Type 1 Preferred

Concept UI: M0225236
Related Numbers: EC 2.7.11.17
Scope Note: A monomeric calcium-calmodulin-dependent protein kinase subtype that is expressed in a broad variety of mammalian cell types. Its expression is regulated by the action of CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE. Several isoforms of this enzyme subtype are encoded by distinct genes.
Terms: Calcium-Calmodulin-Dependent Protein Kinase Type 1 Preferred Term
Term UI T692457
Date02/28/2007
LexicalTag NON
ThesaurusID NLM (2008); CaM Kinase I
Term UI T255239
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2008); Calcium-Dependent CaM Kinase I
Term UI T255240
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2008); Calmodulin-Dependent Protein Kinase I
Term UI T255241
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2008)

Calcium-Calmodulin-Dependent Protein Kinase Type 1 alpha Isoform Narrower

Calcium-Calmodulin-Dependent Protein Kinase Type 1 beta Isoform Narrower

Calcium-Calmodulin-Dependent Protein Kinase Type 1 gamma Isoform Narrower

Calcium-Calmodulin-Dependent Protein Kinase Type 1 delta Isoform Narrower

Calcium-Calmodulin-Dependent Protein Kinase Type 1 MeSH Descriptor Data 2025