MeSH Browser

MeSH Heading: Calcium-Calmodulin-Dependent Protein Kinase Kinase
Tree Number(s): D08.811.913.696.620.682.700.125.049; D12.776.476.563.125.049
Unique ID: D054737
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D054737
Scope Note: A regulatory calcium-calmodulin-dependent protein kinase that specifically phosphorylates CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 4; and PROTEIN KINASE B. It is a monomeric enzyme that is encoded by at least two different genes.
Entry Term(s): CaM Kinase I Activator; CaM-KK; CaM-Kinase Kinase alpha; CaM-Kinase Kinase beta; CaMKK; CaMKKalpha; CaMKKbeta; Calcium-Calmodulin-Dependent Kinase Kinase; Calcium-Calmodulin-Dependent Protein Kinase I Activator; Calcium-Calmodulin-Dependent Protein Kinase Kinase 1; Calcium-Calmodulin-Dependent Protein Kinase Kinase 2; Calcium-Calmodulin-Dependent Protein Kinase Kinase alpha; Calcium-Calmodulin-Dependent Protein Kinase Kinase beta; CamKK-alpha; CamKK-beta
Related Numbers: EC 2.7.11.17
Public MeSH Note: 2008; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE was indexed under PROTEIN-SERINE-THREONINE KINASES 1995-2007
History Note: 2008(1995)
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2021/05/20

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Calcium-Calmodulin-Dependent Protein Kinase Kinase MeSH Descriptor Data 2025