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Myosin-Light-Chain Kinase MeSH Descriptor Data 2023


MeSH Heading
Myosin-Light-Chain Kinase
Tree Number(s)
D08.811.913.696.620.682.700.125.500
D12.776.476.563.125.500
Unique ID
D009219
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D009219
Scope Note
An enzyme that phosphorylates myosin light chains in the presence of ATP to yield myosin-light chain phosphate and ADP, and requires calcium and CALMODULIN. The 20-kDa light chain is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors. The enzyme plays a central role in the regulation of smooth muscle contraction.
Entry Version
MLCK
Entry Term(s)
Myosin Kinase
Myosin LCK
Myosin Regulatory Light-Chain Kinase
Registry Number
EC 2.7.11.18
CAS Type 1 Name
ATP:myosin-light-chain O-phosphotransferase
Previous Indexing
Phosphotransferases, ATP (1966-1972)
Protein Kinases (1973-1986)
Public MeSH Note
87
History Note
87
Date Established
1987/01/01
Date of Entry
1986/06/16
Revision Date
2021/05/21
Myosin-Light-Chain Kinase Preferred
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