MeSH Browser

MeSH Heading: Nuclear Receptor Co-Repressor 2
Tree Number(s): D12.776.930.780.625.400
Unique ID: D056985
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D056985
Scope Note: A nuclear co-repressor protein that shows specificity for RETINOIC ACID RECEPTORS and THYROID HORMONE RECEPTORS. The dissociation of this co-repressor from nuclear receptors is generally ligand-dependent, but can also occur by way of its phosphorylation by members of the MAP KINASE SIGNALING SYSTEM. The protein contains two nuclear receptor interaction domains and four repressor domains and is closely-related in structure to NUCLEAR RECEPTOR CO-REPRESSOR 1.
Entry Term(s): SMRT Co-repressor; Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor; T3 Receptor-associating Factor; TRAC Co-repressor
Registry Number: 0
Public MeSH Note: 2010; NUCLEAR RECEPTOR CO-REPRESSOR 2 was indexed under DNA-BINDING PROTEINS and REPRESSOR PROTEINS 1995-2009
History Note: 2010(1995)
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Revision Date: 2015/06/29

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0533724
Registry Number: 0
Scope Note: A nuclear co-repressor protein that shows specificity for RETINOIC ACID RECEPTORS and THYROID HORMONE RECEPTORS. The dissociation of this co-repressor from nuclear receptors is generally ligand-dependent, but can also occur by way of its phosphorylation by members of the MAP KINASE SIGNALING SYSTEM. The protein contains two nuclear receptor interaction domains and four repressor domains and is closely-related in structure to NUCLEAR RECEPTOR CO-REPRESSOR 1.
Terms: Nuclear Receptor Co-Repressor 2 Preferred Term
Term UI T747631
Date03/16/2009
LexicalTag NON
ThesaurusID NLM (2010); TRAC Co-repressor
Term UI T747714
Date03/17/2009
LexicalTag ABX
ThesaurusID NLM (2010); SMRT Co-repressor
Term UI T747713
Date03/17/2009
LexicalTag ABX
ThesaurusID NLM (2010); Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor
Term UI T747632
Date03/16/2009
LexicalTag NON
ThesaurusID NLM (2010); T3 Receptor-associating Factor
Term UI T747633
Date03/16/2009
LexicalTag NON
ThesaurusID NLM (2010)

Nuclear Receptor Co-Repressor 2 MeSH Descriptor Data 2023