HLA-DR alpha-Chains MeSH Descriptor Data 2024

MeSH Heading: HLA-DR alpha-Chains
Tree Number(s): D09.400.430.890.509.400.440.100; D12.776.395.550.509.400.440.100; D12.776.543.550.440.400.440.100; D23.050.301.500.400.400.440.100; D23.050.301.500.450.400.440.222; D23.050.705.552.410.400.440.100; D23.050.705.552.450.400.440.222
Unique ID: D059805
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D059805
Scope Note: Transmembrane proteins that form the alpha subunits of the HLA-DR antigens. They are also referred to as the HLA-DR heavy chains.
Entry Term(s): HLA Class II Histocompatibility Antigen, DR alpha Chain; HLA-DR Heavy Chain; HLA-DR alpha; HLA-DR alpha-Chain; HLA-DRA; MHC Class II Antigen DRA
Registry Numbers: 0
Previous Indexing: HLA-DR Antigens (1987-2011)
Public MeSH Note: 2012; for HLA-D ALPHA see HLA-DR ANTIGENS 1987-2011; HLA-DRA was indexed under HLA-DR ANTIGENS 1992-2011
History Note: 2012; for HLA-D ALPHA use HLA-DR ANTIGENS 1987-2011
Date Established: 2012/01/01
Date of Entry: 2011/06/24
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Carbohydrates [D09]
- Glycoconjugates [D09.400]
  - Glycoproteins [D09.400.430]
    - Membrane Glycoproteins [D09.400.430.890]
      - Histocompatibility Antigens Class II [D09.400.430.890.509]
        
        HLA-D Antigens [D09.400.430.890.509.400]
        
        HLA-DR Antigens [D09.400.430.890.509.400.440]
        
        HLA-DR alpha-Chains [D09.400.430.890.509.400.440.100]
        
        HLA-DR beta-Chains [D09.400.430.890.509.400.440.200]
        
        HLA-DR Serological Subtypes [D09.400.430.890.509.400.440.400]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Glycoproteins [D12.776.395]
    - Membrane Glycoproteins [D12.776.395.550]
      - Histocompatibility Antigens Class II [D12.776.395.550.509]
        
        HLA-D Antigens [D12.776.395.550.509.400]
        
        HLA-DR Antigens [D12.776.395.550.509.400.440]
        
        HLA-DR alpha-Chains [D12.776.395.550.509.400.440.100]
        
        HLA-DR beta-Chains [D12.776.395.550.509.400.440.200]
        
        HLA-DR Serological Subtypes [D12.776.395.550.509.400.440.400]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Histocompatibility Antigens Class II [D12.776.543.550.440]
        
        HLA-D Antigens [D12.776.543.550.440.400]
        
        HLA-DR Antigens [D12.776.543.550.440.400.440]
        
        HLA-DR alpha-Chains [D12.776.543.550.440.400.440.100]
        
        HLA-DR beta-Chains [D12.776.543.550.440.400.440.200]
        
        HLA-DR Serological Subtypes [D12.776.543.550.440.400.440.400]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Surface [D23.050.301]
    - Histocompatibility Antigens [D23.050.301.500]
      - Histocompatibility Antigens Class II [D23.050.301.500.400]
        
        HLA-D Antigens [D23.050.301.500.400.400]
        
        HLA-DR Antigens [D23.050.301.500.400.400.440]
        
        HLA-DR alpha-Chains [D23.050.301.500.400.400.440.100]
        
        HLA-DR beta-Chains [D23.050.301.500.400.400.440.200]
        
        HLA-DR Serological Subtypes [D23.050.301.500.400.400.440.400]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Surface [D23.050.301]
    - Histocompatibility Antigens [D23.050.301.500]
      - HLA Antigens [D23.050.301.500.450]
        
        HLA-D Antigens [D23.050.301.500.450.400]
        
        HLA-DR Antigens [D23.050.301.500.450.400.440]
        
        HLA-DR alpha-Chains [D23.050.301.500.450.400.440.222]
        
        HLA-DR beta-Chains [D23.050.301.500.450.400.440.333]
        
        HLA-DR Serological Subtypes [D23.050.301.500.450.400.440.389]

Biological Factors [D23]
- Antigens [D23.050]
  - Isoantigens [D23.050.705]
    - Histocompatibility Antigens [D23.050.705.552]
      - Histocompatibility Antigens Class II [D23.050.705.552.410]
        
        HLA-D Antigens [D23.050.705.552.410.400]
        
        HLA-DR Antigens [D23.050.705.552.410.400.440]
        
        HLA-DR alpha-Chains [D23.050.705.552.410.400.440.100]
        
        HLA-DR beta-Chains [D23.050.705.552.410.400.440.200]
        
        HLA-DR Serological Subtypes [D23.050.705.552.410.400.440.389]

Biological Factors [D23]
- Antigens [D23.050]
  - Isoantigens [D23.050.705]
    - Histocompatibility Antigens [D23.050.705.552]
      - HLA Antigens [D23.050.705.552.450]
        
        HLA-D Antigens [D23.050.705.552.450.400]
        
        HLA-DR Antigens [D23.050.705.552.450.400.440]
        
        HLA-DR alpha-Chains [D23.050.705.552.450.400.440.222]
        
        HLA-DR beta-Chains [D23.050.705.552.450.400.440.333]
        
        HLA-DR Serological Subtypes [D23.050.705.552.450.400.440.389]

HLA-DR alpha-Chains Preferred

Concept UI: M0010476
Registry Numbers: 0
Scope Note: Transmembrane proteins that form the alpha subunits of the HLA-DR antigens. They are also referred to as the HLA-DR heavy chains.
Terms: HLA-DR alpha-Chains Preferred Term
Term UI T780631
Date11/16/2010
LexicalTag ABX
ThesaurusID NLM (2012); HLA-DRA
Term UI T234653
Date01/01/1955
LexicalTag ABB
ThesaurusID NLM (2012); HLA-DR alpha-Chain
Term UI T780593
Date11/16/2010
LexicalTag ABX
ThesaurusID NLM (2012); HLA-DR alpha
Term UI T020206
Date08/10/1987
LexicalTag NON
ThesaurusID UNK (19XX); MHC Class II Antigen DRA
Term UI T780595
Date11/16/2010
LexicalTag ACX
ThesaurusID NLM (2012); HLA-DR Heavy Chain
Term UI T780620
Date11/16/2010
LexicalTag ABX
ThesaurusID NLM (2012); HLA Class II Histocompatibility Antigen, DR alpha Chain
Term UI T780594
Date11/16/2010
LexicalTag ABX
ThesaurusID NLM (2012)

page delivered in 0.208s