MeSH Browser

MeSH Heading: HLA-D Antigens
Tree Number(s): D09.400.430.890.509.400; D12.776.395.550.509.400; D12.776.543.550.440.400; D23.050.301.500.400.400; D23.050.301.500.450.400; D23.050.705.552.410.400; D23.050.705.552.450.400
Unique ID: D006681
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D006681
Annotation: general; prefer specifics
Scope Note: Human immune-response or Class II antigens found mainly, but not exclusively, on B-lymphocytes and produced from genes of the HLA-D locus. They are extremely polymorphic families of glycopeptides, each consisting of two chains, alpha and beta. This group of antigens includes the -DR, -DQ and -DP designations, of which HLA-DR is most studied; some of these glycoproteins are associated with certain diseases, possibly of immune etiology.
Entry Term(s): Antigens, HLA-D; Class II Human Antigens; HLA-D; HLA-Dw; HLA-Dw Antigens; Human Class II Antigens; Ia-Like Antigens, Human; Immune Response Associated Antigens, Human; Immune Response-Associated Antigens, Human; Immune-Associated Antigens, Human; Immune-Response Antigens, Human
Previous Indexing: Antigens, Immune Response (1981-1986)
Public MeSH Note: 87; was see ANTIGENS, IMMUNE RESPONSE 1981-86
Online Note: search HISTOCOMPATIBILITY ANTIGENS CLASS II 1981-86
History Note: 87; was see ANTIGENS, IMMUNE RESPONSE 1981-86
Date Established: 1987/01/01
Date of Entry: 1986/06/25
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Carbohydrates [D09]
- Glycoconjugates [D09.400]
  - Glycoproteins [D09.400.430]
    - Membrane Glycoproteins [D09.400.430.890]
      - Histocompatibility Antigens Class II [D09.400.430.890.509]
        
        HLA-D Antigens [D09.400.430.890.509.400]
        
        HLA-DP Antigens [D09.400.430.890.509.400.420]
        
        HLA-DQ Antigens [D09.400.430.890.509.400.430]
        
        HLA-DR Antigens [D09.400.430.890.509.400.440]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Glycoproteins [D12.776.395]
    - Membrane Glycoproteins [D12.776.395.550]
      - Histocompatibility Antigens Class II [D12.776.395.550.509]
        
        HLA-D Antigens [D12.776.395.550.509.400]
        
        HLA-DP Antigens [D12.776.395.550.509.400.420]
        
        HLA-DQ Antigens [D12.776.395.550.509.400.430]
        
        HLA-DR Antigens [D12.776.395.550.509.400.440]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Histocompatibility Antigens Class II [D12.776.543.550.440]
        
        HLA-D Antigens [D12.776.543.550.440.400]
        
        HLA-DP Antigens [D12.776.543.550.440.400.420]
        
        HLA-DQ Antigens [D12.776.543.550.440.400.430]
        
        HLA-DR Antigens [D12.776.543.550.440.400.440]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Surface [D23.050.301]
    - Histocompatibility Antigens [D23.050.301.500]
      - Histocompatibility Antigens Class II [D23.050.301.500.400]
        
        H-2 Antigens [D23.050.301.500.400.199]
        
        HLA-D Antigens [D23.050.301.500.400.400]
        
        HLA-DP Antigens [D23.050.301.500.400.400.420]
        
        HLA-DQ Antigens [D23.050.301.500.400.400.430]
        
        HLA-DR Antigens [D23.050.301.500.400.400.440]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Surface [D23.050.301]
    - Histocompatibility Antigens [D23.050.301.500]
      - HLA Antigens [D23.050.301.500.450]
        
        HLA-A Antigens [D23.050.301.500.450.370]
        
        HLA-B Antigens [D23.050.301.500.450.380]
        
        HLA-C Antigens [D23.050.301.500.450.390]
        
        HLA-D Antigens [D23.050.301.500.450.400]
        
        HLA-DP Antigens [D23.050.301.500.450.400.420]
        
        HLA-DQ Antigens [D23.050.301.500.450.400.430]
        
        HLA-DR Antigens [D23.050.301.500.450.400.440]
        
        HLA-G Antigens [D23.050.301.500.450.700]

Biological Factors [D23]
- Antigens [D23.050]
  - Isoantigens [D23.050.705]
    - Histocompatibility Antigens [D23.050.705.552]
      - Histocompatibility Antigens Class II [D23.050.705.552.410]
        
        H-2 Antigens [D23.050.705.552.410.199]
        
        HLA-D Antigens [D23.050.705.552.410.400]
        
        HLA-DP Antigens [D23.050.705.552.410.400.420]
        
        HLA-DQ Antigens [D23.050.705.552.410.400.430]
        
        HLA-DR Antigens [D23.050.705.552.410.400.440]

Biological Factors [D23]
- Antigens [D23.050]
  - Isoantigens [D23.050.705]
    - Histocompatibility Antigens [D23.050.705.552]
      - HLA Antigens [D23.050.705.552.450]
        
        HLA-A Antigens [D23.050.705.552.450.370]
        
        HLA-B Antigens [D23.050.705.552.450.380]
        
        HLA-C Antigens [D23.050.705.552.450.390]
        
        HLA-D Antigens [D23.050.705.552.450.400]
        
        HLA-DP Antigens [D23.050.705.552.450.400.420]
        
        HLA-DQ Antigens [D23.050.705.552.450.400.430]
        
        HLA-DR Antigens [D23.050.705.552.450.400.440]
        
        HLA-G Antigens [D23.050.705.552.450.700]

HLA-D Antigens Preferred

Concept UI: M0010473
Scope Note: Human immune-response or Class II antigens found mainly, but not exclusively, on B-lymphocytes and produced from genes of the HLA-D locus. They are extremely polymorphic families of glycopeptides, each consisting of two chains, alpha and beta. This group of antigens includes the -DR, -DQ and -DP designations, of which HLA-DR is most studied; some of these glycoproteins are associated with certain diseases, possibly of immune etiology.
Terms: HLA-D Antigens Preferred Term
Term UI T020183
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1987); Human Class II Antigens
Term UI T020179
Date06/25/1986
LexicalTag NON
ThesaurusID UNK (19XX); HLA-D
Term UI T020180
Date03/08/1991
LexicalTag ABB
ThesaurusID NLM (1992); HLA-Dw Antigens
Term UI T020181
Date06/25/1986
LexicalTag NON
ThesaurusID UNK (19XX); Antigens, HLA-D
Term UI T020182
Date03/08/1991
LexicalTag NON
ThesaurusID NLM (1992); HLA-Dw
Term UI T020184
Date05/10/1989
LexicalTag ABB
ThesaurusID NLM (1990); Ia-Like Antigens, Human
Term UI T020185
Date06/25/1986
LexicalTag NON
ThesaurusID UNK (19XX); Immune-Associated Antigens, Human
Term UI T020186
Date06/25/1986
LexicalTag NON
ThesaurusID UNK (19XX); Immune-Response Antigens, Human
Term UI T020187
Date06/25/1986
LexicalTag NON
ThesaurusID UNK (19XX); Immune Response Associated Antigens, Human
Term UI T020188
Date06/25/1986
LexicalTag NON
ThesaurusID UNK (19XX); Class II Human Antigens
Term UI T020178
Date06/25/1986
LexicalTag NON
ThesaurusID UNK (19XX); Immune Response-Associated Antigens, Human
Term UI T020189
Date06/25/1986
LexicalTag NON
ThesaurusID UNK (19XX)

HLA-D Antigens MeSH Descriptor Data 2025