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Endoplasmic Reticulum-Associated Degradation MeSH Descriptor Data 2023


MeSH Heading
Endoplasmic Reticulum-Associated Degradation
Tree Number(s)
G02.111.660.871.790.600.962.500
G02.111.691.600.850.500
G03.734.871.790.600.850.500
G04.434.500.500
G05.308.670.600.850.500
Unique ID
D060746
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D060746
Scope Note
A degradation process whereby incorrectly folded proteins are selectively transported out of the ENDOPLASMIC RETICULUM and into the CYTOSOL. The misfolded proteins are subsequently ubiquitinated and degraded by the PROTEASOME.
Entry Term(s)
ERAD Pathway
Previous Indexing
Protein Folding (1995-2011)
See Also
Endoplasmic Reticulum Stress
Proteolysis
Ubiquitination
Public MeSH Note
2012
History Note
2012
Date Established
2012/01/01
Date of Entry
2011/06/24
Revision Date
2022/07/12
Endoplasmic Reticulum-Associated Degradation Preferred
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