MeSH Browser

MeSH Heading: Hypoxia-Inducible Factor-Proline Dioxygenases
Tree Number(s): D08.811.682.690.416.617.500; D08.811.682.690.708.694.500
Unique ID: D064799
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D064799
Scope Note: Dioxygenase enzymes that specifically hydroxylate a PROLINE residue on the HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT. They are OXYGEN-dependent enzymes that play an important role in mediating cellular adaptive responses to HYPOXIA.
Entry Term(s): Egl Nine Homolog 1 Protein; Egl Nine Homolog 2 Protein; Egl Nine Homolog 3 Protein; HIF Prolyl-4-Hydroxylase; HIF Prolyl-4-Hydroxylases; Hypoxia-Inducible Factor Prolyl Hydroxylase 1; Hypoxia-Inducible Factor Prolyl Hydroxylase 2; Hypoxia-Inducible Factor Prolyl Hydroxylase 3; Hypoxia-Inducible Factor-Proline Dioxygenase
Related Numbers: EC 1.14.11.29
Previous Indexing: Procollagen-Proline Dioxygenase (2004-2013)
Public MeSH Note: 2014
History Note: 2014
Date Established: 2014/01/01
Date of Entry: 2013/07/08
Revision Date: 1955/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Hypoxia-Inducible Factor-Proline Dioxygenases MeSH Descriptor Data 2025