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ADAMTS4 Protein MeSH Descriptor Data 2023


MeSH Heading
ADAMTS4 Protein
Tree Number(s)
D08.811.277.656.675.374.102.500.844
D09.400.430.500.500.844
D12.776.395.033.500.844
D12.776.860.300.085.844
Unique ID
D000071121
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071121
Scope Note
An ADAMTS protease similar to ADAMTS5 PROTEIN. It contains a single C-terminal thrombospondin (TS) motif and cleaves AGGRECAN in CARTILAGE. It may also be involved in the destruction of aggrecan in ARTHRITIS.
Entry Term(s)
A Disintegrin And Metalloproteinase With Thrombospondin Motifs 4 Protein
ADAMTS-4 Protein
Aggrecanase-1
Registry Number
EC 3.4.24.82
Public MeSH Note
2017; ADAMTS4 PROTEIN was indexed under PROCOLLAGEN N-ENDOPEPTIDASE and ADAM PROTEINS 2006-2016; and under METALLOENDOPEPTIDASES 1999-2005
History Note
2017 (1999)
Date Established
2017/01/01
Date of Entry
2016/07/06
Revision Date
2016/02/26
ADAMTS4 Protein Preferred
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