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ADAMTS13 Protein MeSH Descriptor Data 2021


MeSH Heading
ADAMTS13 Protein
Tree Number(s)
D08.811.277.656.675.374.102.500.813
D09.400.430.500.500.813
D12.776.395.033.500.813
D12.776.860.300.085.813
Unique ID
D000071120
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071120
Scope Note
An ADAMTS protease that contains eight thrombospondin (TS) motifs. It cleaves VON WILLEBRAND FACTOR to control vWF-mediated THROMBOSIS. Mutations in the ADAMTS13 gene have been identified in familial cases of PURPURA, THROMBOTIC THROMBOCYTOPENIC and defects in ADAMTS13 activity are associated with MYOCARDIAL INFARCTION; BRAIN ISCHEMIA; PRE-ECLAMPSIA; and MALARIA.
Entry Term(s)
A Disintegrin and Metalloproteinase with Thrombospondin Motifs 13 Protein
ADAMTS-13 Protein
ADAMTS13 Protease
vWF-Cleaving Protease
von Willebrand Factor-Cleaving Protease
Registry Number
EC 3.4.24.87
Previous Indexing
ADAM Proteins (2006-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/06
Revision Date
2016/02/26
ADAMTS13 Protein Preferred
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