A homotypic protein interaction module of the death domain superfamily that is composed of a bundle of six alpha-helices. The death effector domain shares sequence and structural similarities with the DEATH DOMAIN and CASPASE RECRUITMENT DOMAIN. It occurs in many proteins with essential functions in APOPTOSIS.
Entry Term(s)
DED Domain
Previous Indexing
Adaptor Proteins, Signal Transducing (1997-2016)
Amino Acid Sequence (1997-2016)
Death Domain Receptor Signaling Adaptor Proteins (2007-2016)
A homotypic protein interaction module of the death domain superfamily that is composed of a bundle of six alpha-helices. The death effector domain shares sequence and structural similarities with the DEATH DOMAIN and CASPASE RECRUITMENT DOMAIN. It occurs in many proteins with essential functions in APOPTOSIS.
