MeSH Browser

MeSH Heading: Pyrin Domain
Tree Number(s): G02.111.570.820.709.275.750.500.395.875
Unique ID: D000071196
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000071196
Scope Note: A protein interaction domain of the death domain superfamily. It is characterized by a 6-helix bundle similar to those that occur in DEATH DOMAIN RECEPTORS. Pyrin domains are present in a variety of proteins, especially those that function in INFLAMMASOMES; AUTOPHAGY; and APOPTOSIS. They form homodimers or heterodimers with death domain proteins to facilitate the assembly of signaling complexes.
Entry Term(s): DAPIN Domain; PAAD-DAPIN-PYRIN Domain; PADD Domain; PYD Domain
Previous Indexing: Cytoskeletal Proteins (2001-2016); Protein Structure, Tertiary (2001-2016)
See Also: Pyrin
Public MeSH Note: 2017
History Note: 2017
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/05/09

Allowable Qualifiers: drug effects (DE)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Concept UI: M000613569
Scope Note: A protein interaction domain of the death domain superfamily. It is characterized by a 6-helix bundle similar to those that occur in DEATH DOMAIN RECEPTORS. Pyrin domains are present in a variety of proteins, especially those that function in INFLAMMASOMES; AUTOPHAGY; and APOPTOSIS. They form homodimers or heterodimers with death domain proteins to facilitate the assembly of signaling complexes.
Terms: Pyrin Domain Preferred Term
Term UI T000893665
Date01/14/2016
LexicalTag NON
ThesaurusID NLM (2017); PYD Domain
Term UI T000893666
Date01/14/2016
LexicalTag ABX
ThesaurusID NLM (2017); PADD Domain
Term UI T000894913
Date02/08/2016
LexicalTag ACX
ThesaurusID NLM (2017); PAAD-DAPIN-PYRIN Domain
Term UI T000894914
Date02/08/2016
LexicalTag ACX
ThesaurusID NLM (2017); DAPIN Domain
Term UI T000894915
Date02/08/2016
LexicalTag ACX
ThesaurusID NLM (2017)

Pyrin Domain MeSH Descriptor Data 2025