MeSH Browser

MeSH Heading: Receptor, Notch3
Tree Number(s): D12.776.543.750.725.875; D12.776.930.770.875
Unique ID: D000071656
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000071656
Scope Note: A notch receptor characterized by a large extracellular domain containing 34 EPIDERMAL GROWTH FACTOR-like repeats. It functions to regulate CELL DIFFERENTIATION; APOPTOSIS; and CELL PROLIFERATION. Mutations in the EGF repeats of Notch-3 are associated with CADASIL.
Entry Term(s): Neurogenic Locus Notch Homolog Protein 3; Notch-3 Protein; Notch-3 Receptor; Notch3 Protein; Notch3 Receptor
Registry Numbers: 0
Previous Indexing: Receptors, Notch (2006-2016)
Public MeSH Note: 2017
History Note: 2017
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/04/15

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Concept UI: M000615274
Registry Numbers: 0
Scope Note: A notch receptor characterized by a large extracellular domain containing 34 EPIDERMAL GROWTH FACTOR-like repeats. It functions to regulate CELL DIFFERENTIATION; APOPTOSIS; and CELL PROLIFERATION. Mutations in the EGF repeats of Notch-3 are associated with CADASIL.
Terms: Receptor, Notch3 Preferred Term
Term UI T000896245
Date03/01/2016
LexicalTag NON
ThesaurusID NLM (2017); Notch3 Receptor
Term UI T000896251
Date03/01/2016
LexicalTag NON
ThesaurusID NLM (2017); Neurogenic Locus Notch Homolog Protein 3
Term UI T000896246
Date03/01/2016
LexicalTag NON
ThesaurusID NLM (2017); Notch3 Protein
Term UI T000896247
Date03/01/2016
LexicalTag NON
ThesaurusID NLM (2017); Notch-3 Receptor
Term UI T000896249
Date03/01/2016
LexicalTag NON
ThesaurusID NLM (2017); Notch-3 Protein
Term UI T000896250
Date03/01/2016
LexicalTag NON
ThesaurusID NLM (2017)

Receptor, Notch3 MeSH Descriptor Data 2025