MeSH Browser

MeSH Heading: Protein-Arginine Deiminases
Tree Number(s): D08.811.277.721
Unique ID: D000076342
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000076342
Scope Note: A family of ENZYMES that, in the presence of calcium ion, converts ARGININE to CITRULLINE in proteins. There are five PAD isotypes in mammals. In humans: they include PAD1, 2, 3, 4 and 6. They are encoded by five paralogous genes named PADI and clustered on human chromosome 1.
Entry Term(s): Peptidylarginine Deiminase; Peptidylarginine Deiminases; Protein-Arginine Deiminase; Protein-L-Arginine Iminohydrolase; Protein-L-Arginine Iminohydrolases
Registry Number: EC 3.5.3.15
See Also: Citrullination
Public MeSH Note: 2018; PROTEIN-ARGININE DEIMINASE was indexed as HYDROLASES 1987-2017
History Note: 2018 (1987)
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2019/05/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000633135
Registry Number: EC 3.5.3.15
Scope Note: A family of ENZYMES that, in the presence of calcium ion, converts ARGININE to CITRULLINE in proteins. There are five PAD isotypes in mammals. In humans: they include PAD1, 2, 3, 4 and 6. They are encoded by five paralogous genes named PADI and clustered on human chromosome 1.
Terms: Protein-Arginine Deiminases Preferred Term
Term UI T000926812
Date06/13/2017
LexicalTag NON
ThesaurusID NLM (2018); Protein-L-Arginine Iminohydrolase
Term UI T000926816
Date06/13/2017
LexicalTag NON
ThesaurusID NLM (2018); Peptidylarginine Deiminases
Term UI T000926811
Date06/13/2017
LexicalTag NON
ThesaurusID NLM (2018); Protein-L-Arginine Iminohydrolases
Term UI T000926813
Date06/13/2017
LexicalTag NON
ThesaurusID NLM (2018); Protein-Arginine Deiminase
Term UI T000926814
Date06/13/2017
LexicalTag NON
ThesaurusID NLM (2018); Peptidylarginine Deiminase
Term UI T000926815
Date06/13/2017
LexicalTag NON
ThesaurusID NLM (2018)

Protein-Arginine Deiminases MeSH Descriptor Data 2023