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Protein-Arginine Deiminase Type 4 MeSH Descriptor Data 2022


MeSH Heading
Protein-Arginine Deiminase Type 4
Tree Number(s)
D08.811.277.721.500
Unique ID
D000080002
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000080002
Scope Note
A histone modification enzyme, which converts both ARGININE and monomethyl-arginine to CITRULLINE. It is one of several protein-arginine deiminase isoenzymes. It is a gene regulator involved in APOPTOSIS and CELL DIFFERENTIATION and a potential therapeutic target for the treatment of a variety of diseases.
Entry Term(s)
PAD V Enzyme
PADI4 Protein
PADI5 Protein
Peptidyl Arginine Deiminase Type 4
Peptidyl Arginine Deiminase Type IV
Peptidylarginine Deiminase IV
Peptidylarginine Deiminase Type 4
Peptidylarginine Deiminase Type IV
Peptidylarginine Deiminase V
Protein Arginine Deiminase 4
Protein Arginine Deiminase Type 4
Protein Arginine Deiminase Type IV
Protein-Arginine Deiminase Type IV
Registry Number
EC 3.5.3.15
See Also
Citrullination
Public MeSH Note
2020; for PEPTIDYLARGININE DEIMINASE TYPE IV use PROTEIN-ARGININE DEIMINASES 2004-2019; for PEPTIDYLARGININE DEIMINASE V use PROTEIN-ARGININE DEIMINASES 2003-2019
History Note
2020 (2004)
Date Established
2020/01/01
Date of Entry
2019/07/08
Revision Date
2019/05/30
Protein-Arginine Deiminase Type 4 Preferred
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