MeSH Browser

MeSH Heading: Protein-Arginine Deiminase Type 4
Tree Number(s): D08.811.277.721.500
Unique ID: D000080002
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000080002
Scope Note: A histone modification enzyme, which converts both ARGININE and monomethyl-arginine to CITRULLINE. It is one of several protein-arginine deiminase isoenzymes. It is a gene regulator involved in APOPTOSIS and CELL DIFFERENTIATION and a potential therapeutic target for the treatment of a variety of diseases.
Entry Term(s): PAD V Enzyme; PADI4 Protein; PADI5 Protein; Peptidyl Arginine Deiminase Type 4; Peptidyl Arginine Deiminase Type IV; Peptidylarginine Deiminase IV; Peptidylarginine Deiminase Type 4; Peptidylarginine Deiminase Type IV; Peptidylarginine Deiminase V; Protein Arginine Deiminase 4; Protein Arginine Deiminase Type 4; Protein Arginine Deiminase Type IV; Protein-Arginine Deiminase Type IV
See Also: Citrullination
Public MeSH Note: 2020; for PEPTIDYLARGININE DEIMINASE TYPE IV use PROTEIN-ARGININE DEIMINASES 2004-2019; for PEPTIDYLARGININE DEIMINASE V use PROTEIN-ARGININE DEIMINASES 2003-2019
History Note: 2020 (2004)
Date Established: 2020/01/01
Date of Entry: 2019/07/08
Revision Date: 2019/05/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Protein-Arginine Deiminases [D08.811.277.721]

Protein-Arginine Deiminase Type 4 Preferred

Concept UI: M0303511
Scope Note: A histone modification enzyme, which converts both ARGININE and monomethyl-arginine to CITRULLINE. It is one of several protein-arginine deiminase isoenzymes. It is a gene regulator involved in APOPTOSIS and CELL DIFFERENTIATION and a potential therapeutic target for the treatment of a variety of diseases.
Terms: Protein-Arginine Deiminase Type 4 Preferred Term
Term UI T000949398
Date12/07/2018
LexicalTag NON
ThesaurusID NLM (2020); Peptidyl Arginine Deiminase Type IV
Term UI T000950213
Date01/02/2019
LexicalTag NON
ThesaurusID NLM (2020); PADI4 Protein
Term UI T000949719
Date12/14/2018
LexicalTag NON
ThesaurusID NLM (2020); Peptidylarginine Deiminase V
Term UI T000949787
Date12/17/2018
LexicalTag NON
ThesaurusID NLM (2020); PAD V Enzyme
Term UI T000949789
Date12/17/2018
LexicalTag NON
ThesaurusID NLM (2020); PADI5 Protein
Term UI T000949790
Date12/17/2018
LexicalTag NON
ThesaurusID NLM (2020); Peptidyl Arginine Deiminase Type 4
Term UI T000950206
Date01/02/2019
LexicalTag NON
ThesaurusID NLM (2020); Protein Arginine Deiminase Type 4
Term UI T000950207
Date01/02/2019
LexicalTag NON
ThesaurusID NLM (2020); Protein Arginine Deiminase Type IV
Term UI T000950208
Date01/02/2019
LexicalTag NON
ThesaurusID NLM (2020); Protein-Arginine Deiminase Type IV
Term UI T000949412
Date12/07/2018
LexicalTag NON
ThesaurusID NLM (2020); Peptidylarginine Deiminase IV
Term UI T000949403
Date12/07/2018
LexicalTag NON
ThesaurusID NLM (2020); Peptidylarginine Deiminase Type IV
Term UI T000949404
Date12/07/2018
LexicalTag NON
ThesaurusID NLM (2020); Peptidylarginine Deiminase Type 4
Term UI T000949816
Date12/17/2018
LexicalTag NON
ThesaurusID NLM (2020); Protein Arginine Deiminase 4
Term UI T000949411
Date12/07/2018
LexicalTag NON
ThesaurusID NLM (2020)

Protein-Arginine Deiminase Type 4 MeSH Descriptor Data 2025