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Protein-Arginine Deiminase Type 1 MeSH Descriptor Data 2022


MeSH Heading
Protein-Arginine Deiminase Type 1
Tree Number(s)
D08.811.277.721.250
Unique ID
D000080062
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000080062
Scope Note
A peptidylarginine deiminase isoenzyme. It is a post-translational modification enzyme that catalyzes the conversion of protein-bound ARGININE residues to CITRULLINE residues in a CALCIUM ion-dependent manner. It functions within the epidermis, targeting INTERMEDIATE FILAMENTS; KERATINS; and filaggrin for CITRULLINATION to promote epidermal cornification.
Entry Term(s)
PAD Type I
PADI1 Protein
Peptidyl Arginine Deiminase Type 1
Peptidyl Arginine Deiminase Type I
Peptidylarginine Deiminase I
Peptidylarginine Deiminase Type 1
Peptidylarginine Deiminase Type I
Protein Arginine Deiminase 1
Protein Arginine Deiminase Type 1
Protein Arginine Deiminase Type I
Protein-Arginine Deiminase Type I
Registry Number
EC 3.5.3.15
See Also
Citrullination
Public MeSH Note
2020; for PEPTIDYLARGININE DEIMINASE TYPE I see HYDROLASES (1999-2019)
History Note
2020 (1999)
Date Established
2020/01/01
Date of Entry
2019/07/08
Revision Date
2019/05/30
Protein-Arginine Deiminase Type 1 Preferred
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