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Eplerenone MeSH Descriptor Data 2023


MeSH Heading
Eplerenone
Tree Number(s)
D02.540.383
D04.210.500.745.745.329
Unique ID
D000077545
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077545
Scope Note
A spironolactone derivative and selective ALDOSTERONE RECEPTOR antagonist that is used in the management of HYPERTENSION and CONGESTIVE HEART FAILURE, post-MYOCARDIAL INFARCTION.
Entry Term(s)
9,11-Epoxy-7-(methoxycarbonyl)-3-oxo-17-pregn-4-ene-21,17-carbolactone
Eplerenon
Inspra
Pharm Action
Mineralocorticoid Receptor Antagonists
Antihypertensive Agents
Registry Number
6995V82D0B
CAS Type 1 Name
Spiro(cyclopenta(7,8)phenanthro(4b,5-b)oxirene-7(3H),2'(3'H)-furan)-10-carboxylic acid, 2,4,4',4a,5',5a,6,6a,8,9,9a,9b,10,11-tetradecahydro-4a,6a-dimethyl-2,5'-dioxo-, methyl ester, (4aS,4bR,5aR,6aS,7 R,9aS,9bR,10R)-
Public MeSH Note
2019; EPLERENONE was indexed under SPIRONOLACTONE/analogs&derivatives 2000-2018
History Note
2019 (2000)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/04/09
Eplerenone Preferred
Inspra Narrower
9,11-Epoxy-7-(methoxycarbonyl)-3-oxo-17-pregn-4-ene-21,17-carbolactone Related
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