MeSH Browser

MeSH Heading: 4-Butyrolactone
Tree Number(s): D02.540.150; D03.383.312.150
Unique ID: D015107
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015107
Scope Note: One of the FURANS with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent.
Entry Term(s): 1,4-Butanolide; 4-Hydroxybutyric Acid Lactone; Dihydro-2(3H)-furanone; Furanone, tetrahydro-2-; gamma-Butyrolactone
Pharm Action: Solvents
Related Numbers: 96-48-0
CAS Type 1 Name: 2(3H)-Furanone, dihydro-
Previous Indexing: Furans (1969-1975); Lactones (1969-1975)
Public MeSH Note: 91; was see under FURANS 1977-90; was GAMMA BUTYROLACTONE see under FURANS 1976
Online Note: use 4-BUTYROLACTONE to search GAMMA BUTYROLACTONE 1976
History Note: 91(77); was see under FURANS 1977-90; was GAMMA BUTYROLACTONE see under FURANS 1976
Date Established: 1991/01/01
Date of Entry: 1975/07/23
Revision Date: 2016/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0023238
Related Numbers: 96-48-0
Scope Note: One of the FURANS with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent.
Terms: 4-Butyrolactone Preferred Term
Term UI T044122
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1976); 1,4-Butanolide
Term UI T044121
Date07/03/1975
LexicalTag NON
ThesaurusID UNK (19XX); 4-Hydroxybutyric Acid Lactone
Term UI T044123
Date03/23/1977
LexicalTag NON
ThesaurusID UNK (19XX); gamma-Butyrolactone
Term UI T044124
Date05/17/1976
LexicalTag NON
ThesaurusID; Furanone, tetrahydro-2-
Term UI T475140
Date12/28/2001
LexicalTag NON
ThesaurusID NLM (2003); Dihydro-2(3H)-furanone
Term UI T475141
Date12/28/2001
LexicalTag NON
ThesaurusID NLM (2003)

4-Butyrolactone MeSH Descriptor Data 2025