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Orlistat MeSH Descriptor Data 2025


MeSH Heading
Orlistat
Tree Number(s)
D02.540.529
Unique ID
D000077403
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077403
Scope Note
A lactone derivative of LEUCINE that acts as a pancreatic lipase inhibitor to limit the absorption of dietary fat; it is used in the management of obesity.
Entry Term(s)
1-((3-Hexyl-4-oxo-2-oxetanyl)methyl)dodecyl-2-formamido-4-methylvalerate
Alli
Ro-18-0647
THLP
Tetrahydrolipastatin
Tetrahydrolipstatin
Xenical
Pharm Action
Enzyme Inhibitors
Anti-Obesity Agents
Lipid Regulating Agents
Related Numbers
96829-58-2
CAS Type 1 Name
L-Leucine, N-formyl-, 1-((3-hexyl-4-oxo-2-oxetanyl)methyl)dodecyl ester, (2S-(2alpha(R*),3beta))-
Public MeSH Note
2019; ORLISTAT was indexed under LACTONES 1988-2018
History Note
2019 (1988)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/02/27
Orlistat Preferred
Xenical Narrower
Alli Narrower
1-((3-Hexyl-4-oxo-2-oxetanyl)methyl)dodecyl-2-formamido-4-methylvalerate Related
Ro-18-0647 Narrower
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