Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

Orlistat MeSH Descriptor Data 2026


MeSH Heading
Orlistat
Tree Number(s)
D02.540.529
Unique ID
D000077403
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077403
Scope Note
A lactone derivative of LEUCINE that acts as a pancreatic lipase inhibitor to limit the absorption of dietary fat; it is used in the management of obesity.
Entry Term(s)
1-((3-Hexyl-4-oxo-2-oxetanyl)methyl)dodecyl-2-formamido-4-methylvalerate
Alli
Ro-18-0647
THLP
Tetrahydrolipastatin
Tetrahydrolipstatin
Xenical
Pharm Action
Enzyme Inhibitors
Anti-Obesity Agents
Lipid Regulating Agents
Registry Numbers
95M8R751W8
0
Related Numbers
96829-58-2
CAS Type 1 Name
L-Leucine, N-formyl-, 1-((3-hexyl-4-oxo-2-oxetanyl)methyl)dodecyl ester, (2S-(2alpha(R*),3beta))-
Public MeSH Note
2019; ORLISTAT was indexed under LACTONES 1988-2018
History Note
2019 (1988)
Date Introduced
2019/01/01
Last Updated
2019/01/01
Orlistat Preferred
Xenical Narrower
Alli Narrower
1-((3-Hexyl-4-oxo-2-oxetanyl)methyl)dodecyl-2-formamido-4-methylvalerate Related
Ro-18-0647 Narrower
page delivered in 0.147s