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Homoharringtonine MeSH Descriptor Data 2024


MeSH Heading
Homoharringtonine
Tree Number(s)
D03.132.420.500
D03.633.100.079.533.500
D03.633.400.624.500
Unique ID
D000077863
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077863
Scope Note
Semisynthetic derivative of harringtonine that acts as a protein synthesis inhibitor and induces APOPTOSIS in tumor cells. It is used in the treatment of MYELOID LEUKEMIA, CHRONIC.
Entry Term(s)
Ceflatonin
Cephalotaxine
Homoharringtonine (3(R))-isomer
Omacetaxine
Omacetaxine Mepesuccinate
Synribo
Pharm Action
Antineoplastic Agents, Phytogenic
Protein Synthesis Inhibitors
Registry Numbers
6FG8041S5B
84MI6OYN4Z
0
Related Numbers
24316-19-6
26833-87-4
84MI6OYN4Z
CAS Type 1 Name
Cephalotaxine, O3-((2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methyl-1-oxoheptyl)-
Public MeSH Note
2019; HOMOHARRINGTONINE was indexed under HARRINGTONINES 1978-2018; under ALKALOIDS and ANTINEOPLASTIC AGENTS 1972-1977; and under DIOXOLES 1972-1976
History Note
2019 (1972)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/05/21
Homoharringtonine Preferred
Cephalotaxine Narrower
Ceflatonin Narrower
Synribo Narrower
Homoharringtonine (3(R))-isomer Narrower
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