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HLA-E Antigens MeSH Descriptor Data 2025


MeSH Heading
HLA-E Antigens
Tree Number(s)
D09.400.430.890.489.850
D12.776.395.550.489.850
D12.776.543.550.439.850
D23.050.301.500.100.850
D23.050.705.552.100.850
Unique ID
D000097625
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000097625
Scope Note
Class I human histocompatibility (HLA) antigens encoded by genes at the E locus on chromosome 6. They bind a restricted subset of peptides derived from the leader peptides of other class I molecules. They primarily are involved with down-regulating cytolytic activity of NK CELLS and restricting non-canonical CD8-POSITIVE T LYMPHOCYTES.
Entry Term(s)
HLA E Antigens
HLA E*0101 antigen
HLA-E 0103 antigen
HLA-E*0101 antigen
HLA-E*0103
HLA-E*01:01 antigen
HLA-E*01:03 antigen
Public MeSH Note
2024: HLA-E ANTIGEN was indexed under HISTOCOMPATIBILITY ANTIGENS CLASS I 1989-2023, and under HLA ANTIGENS 1988-1988
History Note
2024 (1988)
Date Established
2024/01/01
Date of Entry
2023/07/26
Revision Date
2023/06/14
HLA-E Antigens Preferred
HLA-E*01:03 antigen Narrower
HLA-E*01:01 antigen Narrower
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