MeSH Browser

MeSH Heading: Porphobilinogen Synthase
Tree Number(s): D08.811.520.241.300.550
Unique ID: D000623
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000623
Scope Note: An enzyme that catalyzes the formation of porphobilinogen from two molecules of 5-aminolevulinic acid. EC 4.2.1.24.
Entry Term(s): ALA-Dehydrase; Aminolevulinate Hydro-Lyase; Aminolevulinic Acid Dehydratase; delta-Aminolevulinate Dehydratase; delta-Aminolevulinic Acid Dehydratase
Registry Number: EC 4.2.1.24
Related Numbers: 9036-37-7
CAS Type 1 Name: 5-Aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing)
Previous Indexing: Hydro-Lyases (1966-1972)
Public MeSH Note: 98; see AMINOLEVULINIC ACID DEHYDRATASE 1978-97, see HYDRO-LYASES 1973-77
History Note: 98(73)
Date Established: 1978/01/01
Date of Entry: 1999/01/01
Revision Date: 2003/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0000953
Registry Number: EC 4.2.1.24
Related Numbers: 9036-37-7
Scope Note: An enzyme that catalyzes the formation of porphobilinogen from two molecules of 5-aminolevulinic acid. EC 4.2.1.24.
Terms: Porphobilinogen Synthase Preferred Term
Term UI T001865
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1973); Aminolevulinate Hydro-Lyase
Term UI T001861
Date05/23/1977
LexicalTag NON
ThesaurusID UNK (19XX); delta-Aminolevulinate Dehydratase
Term UI T001863
Date12/18/1981
LexicalTag NON
ThesaurusID UNK (19XX); delta-Aminolevulinic Acid Dehydratase
Term UI T001864
Date08/07/1981
LexicalTag NON
ThesaurusID UNK (19XX); ALA-Dehydrase
Term UI T001860
Date03/02/1982
LexicalTag NON
ThesaurusID UNK (19XX); Aminolevulinic Acid Dehydratase
Term UI T001862
Date11/15/1996
LexicalTag NON
ThesaurusID NLM (1998)

Porphobilinogen Synthase MeSH Descriptor Data 2023