NLM Logo

Cystathionine beta-Synthase MeSH Descriptor Data 2023


MeSH Heading
Cystathionine beta-Synthase
Tree Number(s)
D08.811.520.241.300.200
Unique ID
D003541
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D003541
Annotation
/defic: consider also HOMOCYSTINURIA or HYPERHOMOCYSTEINEMIA
Scope Note
A multifunctional pyridoxal phosphate enzyme. In the second stage of cysteine biosynthesis it catalyzes the reaction of homocysteine with serine to form cystathionine with the elimination of water. Deficiency of this enzyme leads to HYPERHOMOCYSTEINEMIA and HOMOCYSTINURIA. EC 4.2.1.22.
Entry Term(s)
Cystathionine Synthetase
Serine Sulfhydrase
beta-Thionase
Registry Number
EC 4.2.1.22
Related Numbers
9023-99-8
CAS Type 1 Name
L-Serine hydro-lyase (adding homocysteine)
Previous Indexing
Homocysteine (1973-1974)
Hydro-Lyases (1973-1974)
Serine (1973-1974)
See Also
Homocystinuria
Public MeSH Note
1991; see HYDRO-LYASES 1975-1990
History Note
1991(1975)
Date Established
1991/01/01
Date of Entry
1974/11/11
Revision Date
2003/07/09
Cystathionine beta-Synthase Preferred
page delivered in 0.162s