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Fumarate Hydratase
MeSH Descriptor Data 2025
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Fumarate Hydratase
Tree Number(s)
D08.811.520.241.300.300
Unique ID
D005649
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D005649
Scope Note
An enzyme that catalyzes the reversible hydration of fumaric acid to yield L-malic acid. It is one of the citric acid cycle enzymes. EC 4.2.1.2.
Entry Term(s)
Fumarase
Related Numbers
9032-88-6
CAS Type 1 Name
(S)-Malate hydro-lyase
Previous Indexing
Hydro-Lyases (1966-1972)
Public MeSH Note
78; was see under HYDRO-LYASES 1975-77
History Note
78(73); was see under HYDRO-LYASES 1975-77
Date Established
1978/01/01
Date of Entry
1999/01/01
Revision Date
2003/07/09
Allowable Qualifiers
administration & dosage (AD)
adverse effects (AE)
analysis (AN)
antagonists & inhibitors (AI)
biosynthesis (BI)
blood (BL)
cerebrospinal fluid (CF)
chemical synthesis (CS)
chemistry (CH)
classification (CL)
deficiency (DF)
drug effects (DE)
economics (EC)
genetics (GE)
history (HI)
immunology (IM)
isolation & purification (IP)
metabolism (ME)
pharmacokinetics (PK)
pharmacology (PD)
physiology (PH)
poisoning (PO)
radiation effects (RE)
standards (ST)
supply & distribution (SD)
therapeutic use (TU)
toxicity (TO)
ultrastructure (UL)
urine (UR)
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Lyases [D08.811.520]
Carbon-Oxygen Lyases [D08.811.520.241]
Hydro-Lyases [D08.811.520.241.300]
Aconitate Hydratase [D08.811.520.241.300.050]
Carbonic Anhydrases [D08.811.520.241.300.150]
Cystathionine beta-Synthase [D08.811.520.241.300.200]
Enoyl-CoA Hydratase [D08.811.520.241.300.250]
Enoyl-CoA Hydratase 2 [D08.811.520.241.300.275]
Fatty Acid Synthases [D08.811.520.241.300.287]
Fumarate Hydratase [D08.811.520.241.300.300]
Phosphopyruvate Hydratase [D08.811.520.241.300.500]
Porphobilinogen Synthase [D08.811.520.241.300.550]
Prephenate Dehydratase [D08.811.520.241.300.600]
Propanediol Dehydratase [D08.811.520.241.300.650]
Tryptophan Synthase [D08.811.520.241.300.850]
Urocanate Hydratase [D08.811.520.241.300.900]
Uroporphyrinogen III Synthetase [D08.811.520.241.300.950]
Expand All
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Fumarate Hydratase
Preferred
Concept UI
M0008879
Related Numbers
9032-88-6
Scope Note
An enzyme that catalyzes the reversible hydration of fumaric acid to yield L-malic acid. It is one of the citric acid cycle enzymes. EC 4.2.1.2.
Terms
Fumarate Hydratase
Preferred Term
Term UI
T017088
Date
01/01/1999
LexicalTag
NON
ThesaurusID
NLM (1973)
Fumarase
Term UI
T017087
Date
04/08/1977
LexicalTag
NON
ThesaurusID
UNK (19XX)
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