MeSH Browser

MeSH Heading: Enoyl-CoA Hydratase
Tree Number(s): D08.811.520.241.300.250
Unique ID: D004746
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D004746
Scope Note: An enzyme that catalyzes reversibly the hydration of unsaturated fatty acyl-CoA to yield beta-hydroxyacyl-CoA. It plays a role in the oxidation of fatty acids and in mitochondrial fatty acid synthesis, has broad specificity, and is most active with crotonyl-CoA. EC 4.2.1.17.
Entry Term(s): 3-Hydroxyacyl CoA Hydrolyases; 3-Hydroxyacyl Dehydratases; Crotonase; Enoyl CoA Hydratases; Enoyl Hydrase; beta-Hydroxyacyl Dehydratases; beta-Hydroxyacyl-CoA Dehydrases; trans-2-Enoyl-Coenzyme A Hydratase
Registry Numbers: EC 4.2.1.17
Related Numbers: 9027-13-8
CAS Type 1 Name: (3S)-3-Hydroxyacyl-CoA hydro-lyase
Previous Indexing: Coenzyme A (1966-1977); Hydro-Lyases (1966-1977)
Public MeSH Note: 97; was ENOYL COA HYDRATASES 1978-96 (see under HYDRO-LYASES 1978-90)
History Note: 97; was ENOYL COA HYDRATASES 1978-96 (see under HYDRO-LYASES 1978-90)
Date Established: 1991/01/01
Date of Entry: 1977/05/20
Revision Date: 2016/06/28

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0007457
Registry Numbers: EC 4.2.1.17
Related Numbers: 9027-13-8
Scope Note: An enzyme that catalyzes reversibly the hydration of unsaturated fatty acyl-CoA to yield beta-hydroxyacyl-CoA. It plays a role in the oxidation of fatty acids and in mitochondrial fatty acid synthesis, has broad specificity, and is most active with crotonyl-CoA. EC 4.2.1.17.
Terms: Enoyl-CoA Hydratase Preferred Term
Term UI T014510
Date01/01/1999
LexicalTag ABX
ThesaurusID NLM (1978); 3-Hydroxyacyl Dehydratases
Term UI T014505
Date05/20/1977
LexicalTag NON
ThesaurusID UNK (19XX); beta-Hydroxyacyl Dehydratases
Term UI T014506
Date05/20/1977
LexicalTag NON
ThesaurusID UNK (19XX); beta-Hydroxyacyl-CoA Dehydrases
Term UI T014507
Date07/31/1980
LexicalTag NON
ThesaurusID UNK (19XX); Crotonase
Term UI T014508
Date05/20/1977
LexicalTag NON
ThesaurusID UNK (19XX); Enoyl CoA Hydratases
Term UI T014509
Date12/13/1995
LexicalTag NON
ThesaurusID NLM (1997); Enoyl Hydrase
Term UI T014511
Date05/20/1977
LexicalTag NON
ThesaurusID UNK (19XX); 3-Hydroxyacyl CoA Hydrolyases
Term UI T014504
Date05/20/1977
LexicalTag NON
ThesaurusID UNK (19XX); trans-2-Enoyl-Coenzyme A Hydratase
Term UI T014512
Date10/08/1986
LexicalTag NON
ThesaurusID UNK (19XX)

Enoyl-CoA Hydratase MeSH Descriptor Data 2025