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Apolipoproteins E MeSH Descriptor Data 2023


MeSH Heading
Apolipoproteins E
Tree Number(s)
D10.532.091.500
D12.776.070.400.500
D12.776.521.120.500
Unique ID
D001057
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D001057
Scope Note
A class of protein components which can be found in several lipoproteins including HIGH-DENSITY LIPOPROTEINS; VERY-LOW-DENSITY LIPOPROTEINS; and CHYLOMICRONS. Synthesized in most organs, Apo E is important in the global transport of lipids and cholesterol throughout the body. Apo E is also a ligand for LDL receptors (RECEPTORS, LDL) that mediates the binding, internalization, and catabolism of lipoprotein particles in cells. There are several allelic isoforms (such as E2, E3, and E4). Deficiency or defects in Apo E are causes of HYPERLIPOPROTEINEMIA TYPE III.
Entry Term(s)
Apo E
Apo E Isoproteins
Apo-E
ApoE
Apolipoprotein E Isoproteins
Apoprotein (E)
Apoproteins E
Registry Number
0
Previous Indexing
Apolipoproteins (1977-1984)
Public MeSH Note
1985; APOLIPOPROTEIN E ISOPROTEINS was indexed under APOLIPOPROTEINS E 1985-2006 & under APOLIPOPROTEINS 1983-1984
History Note
1985; for APOLIPOPROTEIN E ISOPROTEINS use APOLIPOPROTEINS E 1985-2006 & use APOLIPOPROTEINS 1983-1984
Date Established
1985/01/01
Date of Entry
1984/05/25
Revision Date
2006/07/05
Apolipoproteins E Preferred
Apolipoprotein E Isoproteins Narrower
Apoproteins E Broader
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