MeSH Browser

MeSH Heading: Biguanides
Tree Number(s): D02.078.370.141
Unique ID: D001645
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D001645
Scope Note: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
Entry Term(s): Biguanide
Pharm Action: Hypoglycemic Agents
Public MeSH Note: 66
History Note: 66(65)
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Biguanides MeSH Descriptor Data 2025