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3-Iodobenzylguanidine MeSH Descriptor Data 2023


MeSH Heading
3-Iodobenzylguanidine
Tree Number(s)
D02.078.370.510
D02.455.426.559.389.454.300
D02.455.526.581.496.300
Unique ID
D019797
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019797
Scope Note
A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. (Merck Index, 12th ed) MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase.
Entry Term(s)
(3-Iodo-(131I)benzyl)guanidine
3-Iodobenzylguanidine, 123I Labeled
3-Iodobenzylguanidine, 125I Labeled
Iobenguane
Iobenguane (131I)
MIBG
m-Iodobenzylguanidine
meta-Iodobenzylguanidine
Pharm Action
Antineoplastic Agents
Enzyme Inhibitors
Radiopharmaceuticals
Registry Number
35MRW7B4AD
Related Numbers
74075-13-1
76924-93-1
77679-27-7
Q461L7AK4R
Previous Indexing
Guanidines (1980-1982)
Iodobenzenes (1983-1997)
Public MeSH Note
98; 3-IODOBENZYLGUANIDINE was indexed under IODOBENZENES 1983-97 & GUANIDINES 1980-82
History Note
98; use 3-IODOBENZYLGUANIDINE (NM) 1980-97
Date Established
1998/01/01
Date of Entry
1997/06/20
Revision Date
2013/07/08
3-Iodobenzylguanidine Preferred
Iobenguane (131I) Narrower
3-Iodobenzylguanidine, 125I Labeled Narrower
(3-Iodo-(131I)benzyl)guanidine Narrower
3-Iodobenzylguanidine, 123I Labeled Narrower
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