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Guanethidine MeSH Descriptor Data 2023


MeSH Heading
Guanethidine
Tree Number(s)
D02.078.370.460
Unique ID
D006145
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D006145
Scope Note
An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
Entry Term(s)
((2-Hexahydro-1(2H)-azocinyl)ethyl)guanidine
Guanethidine Monosulfate
Guanethidine Sulfate
Guanethidine Sulfate (1:1)
Guanethidine Sulfate (1:2)
Guanethidine Sulfate (2:1)
Guanethidine Sulfate (2:1), 14C-Labeled
Ismelin
Isobarin
Octadine
Oktadin
Pharm Action
Antihypertensive Agents
Sympatholytics
Adrenergic Agents
Registry Number
ZTI6C33Q2Q
Related Numbers
14920-15-1
55-65-2
5UBY8Y002G
60-02-6
645-43-2
87862-38-2
8AQ60474G9
CAS Type 1 Name
Guanidine, (2-(hexahydro-1(2H)-azocinyl)ethyl)-
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2013/07/08
Guanethidine Preferred
Guanethidine Sulfate Narrower
Guanethidine Sulfate (1:2) Narrower
Ismelin Narrower
Isobarin Narrower
Guanethidine Monosulfate Narrower
Guanethidine Sulfate (2:1), 14C-Labeled Narrower
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