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Busulfan MeSH Descriptor Data 2021


MeSH Heading
Busulfan
Tree Number(s)
D02.033.455.125.125
D02.455.326.146.100.050.500.100
D02.886.645.600.055.050.510.100
Unique ID
D002066
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D002066
Scope Note
An alkylating agent having a selective immunosuppressive effect on BONE MARROW. It has been used in the palliative treatment of chronic myeloid leukemia (MYELOID LEUKEMIA, CHRONIC), but although symptomatic relief is provided, no permanent remission is brought about. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen.
Entry Term(s)
Busulfan Wellcome
Busulfex
Busulphan
Glyzophrol
Myelosan
Mylecytan
Myleran
Myléran
n-Butane-1,3-di(methylsulfonate)
Pharm Action
Alkylating Agents
Immunosuppressive Agents
Antineoplastic Agents, Alkylating
Myeloablative Agonists
Registry Number
G1LN9045DK
Related Numbers
55-98-1
CAS Type 1 Name
1,4-Butanediol, dimethanesulfonate
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2016/07/05
Busulfan Preferred
Busulfan Wellcome Narrower
Busulfex Narrower
Myleran Narrower
Myelosan Narrower
Mylecytan Narrower
n-Butane-1,3-di(methylsulfonate) Related
Glyzophrol Narrower
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